词条 | Trifluoromethoxy |
释义 |
Trifluoromethoxy is the chemical group –O–{{chem|CF|3}}. It can be seen as a methoxy group –O–{{chem|CH|3}} whose hydrogen atoms are replaced by fluorine atoms; or as a trifluoromethyl group attached to the rest of the molecule by a bridging oxygen atom.[1] Compounds having this functional group are of some relevance as pharmaceuticals. One example is riluzole. See also
References1. ^Synthetic Approaches to Trifluoromethoxy-Substituted Compounds A. Tlili, F. Toulgoat, T. Billard, Angew. Chem. Int. Ed. 2016, 55, 11726. {{DOI|10.1002/anie.201603697}} {{organohalide-stub}} 2 : Haloalkyl groups|Trifluoromethyl compounds |
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