| 词条 | TSUP family |
| 释义 |
The 4-Toluene Sulfonate Uptake Permease (TSUP) family (TC# 2.A.102) is also referred to as the TauE/SafE/YfcA/DUF81 Family. Although its members have not been rigorously characterized, evidence is available that at least some members function in the transport of sulfur containing organic compounds. These include 4-toluene sulfonate which may be transported by the TsaS of Cupriavidus necator (TC# 2.A.102.1.1), sulfolactate which may be exported by the TauE protein of Cupriavidus necator (TC# 2.A.102.2.1) [1][2] and sulfoacetate which may be exported by the SafE1 protein of Neptuniibacter caesariensis (TC# 2.A.102.2.2).[3] Another member of the TSUP family, TsaS of Comamonas testosteroni, has been reported to function in the uptake of 4-toluene sulfonate.[4] None of these functional assignments can be considered to be certain.[5] References1. ^{{cite journal|last1=Weinitschke|first1=S|last2=Denger|first2=K|last3=Cook|first3=AM|last4=Smits|first4=TH|title=The DUF81 protein TauE in Cupriavidus necator H16, a sulfite exporter in the metabolism of C2 sulfonates.|journal=Microbiology|date=September 2007|volume=153|issue=9|pages=3055–60|pmid=17768248|doi=10.1099/mic.0.2007/009845-0}} 2. ^{{cite journal|last1=Mayer|first1=J|last2=Denger|first2=K|last3=Hollemeyer|first3=K|last4=Schleheck|first4=D|last5=Cook|first5=AM|title=(R)-Cysteate-nitrogen assimilation by Cupriavidus necator H16 with excretion of 3-sulfolactate: a patchwork pathway.|journal=Archives of Microbiology|date=November 2012|volume=194|issue=11|pages=949–57|doi=10.1007/s00203-012-0825-y|pmid=22797525|url=https://zenodo.org/record/1239682|type=Submitted manuscript}} 3. ^{{cite journal|last1=Krejcík|first1=Z|last2=Denger|first2=K|last3=Weinitschke|first3=S|last4=Hollemeyer|first4=K|last5=Paces|first5=V|last6=Cook|first6=AM|last7=Smits|first7=TH|title=Sulfoacetate released during the assimilation of taurine-nitrogen by Neptuniibacter caesariensis: purification of sulfoacetaldehyde dehydrogenase.|journal=Archives of Microbiology|date=August 2008|volume=190|issue=2|pages=159–68|doi=10.1007/s00203-008-0386-2|pmid=18506422|url=http://nbn-resolving.de/urn:nbn:de:bsz:352-opus-67590|type=Submitted manuscript}} 4. ^{{cite journal|last1=Mampel|first1=J|last2=Maier|first2=E|last3=Tralau|first3=T|last4=Ruff|first4=J|last5=Benz|first5=R|last6=Cook|first6=AM|title=A novel outer-membrane anion channel (porin) as part of a putatively two-component transport system for 4-toluenesulphonate in Comamonas testosteroni T-2.|journal=Biochemical Journal|date=October 1, 2004|volume=383|issue=1|pages=91–9|pmid=15176949|doi=10.1042/bj20040652|pmc=1134047}} 5. ^{{cite web|last1=Saier|first1=MH Jr.|title=2.A.102. The 4-Toluene Sulfonate Uptake Permease (TSUP) Family|url=http://tcdb.org/search/result.php?tc=2.A.102|website=Transporter Classification Database|publisher=Saier Lab Bioinformatics Group}} Further reading{{refbegin|30em}}
7 : Protein families|Membrane proteins|Biology|Transmembrane proteins|Transmembrane transporters|Transport proteins|Integral membrane proteins |
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