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词条 Una Ryan
释义

  1. Biography

  2. Selected works

  3. References

  4. Bibliography

  5. External links

{{about|the American biologist|the Irish biochemist|Una M. Ryan}}{{Infobox person
|name = Una Ryan
|image =
|image_size =
|caption =
|birth_name = Una Scully
|birth_date = {{birth date and age|df=y|1941|12|18}}
|birth_place = Kuala Lumpur, Malaysia
|nationality = British-American
|other_names = Una S. Smith, Una Scully Ryan, Una Callow
|alma_mater = University of Bristol
University of Cambridge
|employer = University of Miami
Washington University School of Medicine/Monsanto
Boston University/AVANT Immunotherapeutics Inc
Bay Area BioEconomy Initiative
|occupation = vascular biology, biotechnology angel investing
|years_active = 1964–
|spouse = Smith (ca. 1965)
Ryan (ca. 1975)
Allan Dana Callow (m. May 26, 1989)
}}

Una Ryan (born December 18, 1941) is a British-American biologist who has conducted research on vascular biology, publishing over 300 papers. After an extended research and academic career she began a career in the biotech industry. She was Director for Health Sciences of Monsanto Company; CEO, president and director of AVANT Immunotherapeutics; and is currently the Chairman of The Bay Area BioEconomy Initiative, among many other associations. She is an angel investor and focuses her funds on women-led companies. She has won numerous awards and recognition during her career including the National Institute of Health's 10-year merit award, Order of the British Empire and the Albert Einstein Award.

Biography

Una Scully was born on December 18, 1941[1] in Kuala Lumpur, Malaysia to a British father who was interned in a Japanese camp during World War II. Scully and her mother fled by boat from Singapore to England, where she completed her education, graduating with a degree in zoology from the University of Bristol in 1963.[2] In 1965, she began publishing under the name of Una Smith and did so until 1973.[1][3] She went on to complete a PhD at the University of Cambridge in 1967 and that same year moved to the United States, taking up a Howard Hughes Fellowship at the University of Miami to study angiotensin-converting enzymes.[2] After completion of the fellowship, Smith taught as a professor of life sciences and medicine at the University of Miami School of Medicine from 1972 to 1989.[4] In 1975, her professional publishing reflected her name as U. S. Ryan or Una Scully Ryan.[1][5] Her work at Miami was recognized by a 10-year Merit Award from the National Institutes of Health.[2]

In 1989, Ryan married the surgeon, Allan Dana Callow{{sfn|Callow|2013|p=xiii}} and then beginning in 1990, she worked as a Research Professor of Surgery, Medicine and Cell Biology at Washington University School of Medicine in St. Louis, Missouri. Simultaneously, she accepted a position at Monsanto as Director for Health Sciences. She left Monsanto in 1992 and joined AVANT Immunotherapeutics Inc. as a Vice-President and Chief Scientific Researcher in May 1993.[4] Around the same time, she left Washington University for a position as a Research Professor of Medicine at Boston University School of Medicine and obtained US citizenship in 1994.[6] In 1996, Ryan was promoted to President at AVANT and also began serving as chief executive officer and President of Celldex Therapeutics Inc.,[4] all the while continuing to research and publish papers on vaccines against viral and bacterial diseases and for cholesterol management.[6]

Ryan was awarded the Order of the British Empire in 2002 for her contributions to research and development to biotechnology.[6] In 2007, she was honored with the Albert Einstein Award for her development of new vaccines to combat global infectious diseases[2] and then in 2008, she left the for-profit sector leaving her positions at AVANT and Celldex.[4] In 2009 she was awarded an honorary doctorate from the University of Bristol.[2] In addition to vaccines, Ryan has worked on clean water solutions and in 2009 was awarded a Cartier Women's Initiative Awards for a wastewater cleaning program using blue-green algae and solar energy.[7] Unable to secure venture capital funds for the program, Ryan turned her focus toward a program called Diagnostics for All, in an attempt to provide inexpensive diagnostic tests to developing countries. The innovation used paper tests and a drop of blood which when chemicals were applied would change color to indicate different results, without lab work required and simple disposal, as the paper could be burned.[8] The company began with liver testing and then expanded their products to include pregnancy tests and a glucose monitoring test for diabetics.[9]

Deciding to relocate to the American west coast in 2013, Ryan accepted a position as the first woman to Chair the Bay Area BioEconomy Initiative. While she was in Boston, Ryan had served on the board of the Biotechnology Industry Organization and the BioEconomy Initiative had similar aims of increasing efficiency and decreasing the time it takes for products to begin clinical trials and ultimately get to medical professionals. She also turned her focus to angel investing in an attempt to help women-run businesses find venture capital funds. Ryan served as managing director of Golden Seeds, as a partner in Astia Angel and participated with The Angel Forum all aimed at investing in startups and mentoring businesses in the Silicon Valley.[10] She continues to serve on the boards of several biotechnology firms.[4]

In 2015, Ryan launched ULUX fine art based on her electron micrographs. Ryan has two daughters, Tamsin Smith, a poet and social impact innovator, who helped create and served as founding president of Bono's Product Red initiative. Daughter Amy Ryan Dowsett is an interior designer. Both daughters live in San Francisco, CA. Ryan has four grandchildren.

Selected works

  • {{cite journal |last=Scully|first=Una|date=February 1964|title=Factors influencing the secretion of regeneration-promoting hormone in Nereis diversicolor|journal=General and Comparative Endocrinology|volume=4|issue=1|pages=91–98 |doi=10.1016/0016-6480(64)90041-3}}
  • {{cite journal |last=Scully|first=Una|date=February 1964|title=Hormonal control of growth in Nereis diversicolor|doi= 10.1016/0016-6480(64)90040-1|journal=General and Comparative Endocrinology|volume=4|issue=1|pages=82–90}}
  • {{cite journal |last1=Smith|first1=Una|last2=Smith|first2=David S|date=September 1965|title=A mictotubular complex in the epidermal nucleus of an insect, Carausius morosus|journal=Journal of Cell Biology|volume=26|issue=3|pages=961–967|doi=10.1083/jcb.26.3.961}}
  • {{cite journal |last1=Smith|first1=Una|last2=Ribbons|first2=Douglas W|last3=Smith|first3=David S|year=1970|title=The fine structure of Methylococcus capsulatus|journal=Tissue and Cell|volume=2|issue=4|pages=513–520 |doi=10.1016/s0040-8166(70)80027-1}}
  • {{cite journal |last1=Smith|first1=Una|last2=Smith|first2=David S|last3=Ryan|first3=James W|date=May 1973|title=Tubular myelin assembly in type II alveolar cells: Freeze-fracture studies|journal=The Anatomical Record|volume=176|issue=1|pages=125–127 |doi=10.1002/ar.1091760110}}
  • {{cite journal |last1=Ryan|first1=Una|last2=Ryan|first2=James W|last3=Smith|first3=David S|year=1975|title=Alveolar type II cells: Studies on the mode of release of lamellar bodies|journal=Tissue and Cell|volume=7|issue=3|pages=587–599 |doi=10.1016/0040-8166(75)90028-2}}
  • {{cite journal |last1=Ryan|first1=Una|last2=Ryan|first2=James W|date=July 1976|title=Correlation of pulmonary structure with pharmacokinetic function|journal=Agents and Actions|volume=6|issue=4|pages=510–515 |doi=10.1007/bf01973270}}
  • {{cite journal |last1=Ryan|first1=Una|last2=Ryan|first2=James W|date=April 1980|title=Angiotensin-Converting Enzyme: II. Pulmonary Endothelial Cells in Culture|journal=Environmental Health Perspectives|volume=35|pages=171–180 |doi=10.1289/ehp.8035171}}
  • {{cite journal |last1=Jacobson|first1=Bruce S|last2=Ryan|first2=Una|year=1982|title=Growth of endothelial and HeLa cells on a new multipurpose microcarrier that is positive, negative or collagen coated|journal=Tissue and Cell|volume=4|issue=1|pages=69–83|doi=10.1016/0040-8166(82)90008-8}}
  • {{cite journal |last1=Ryan|first1=Una|date=June 1984|title=Isolation and Culture of Pulmonary Endothelial Cells|journal=Environmental Health Perspectives|volume=56|pages=103–114 |doi=10.1289/ehp.8456103|pmid=6090112}}
  • {{cite journal |last1=Ryan|first1=Una|year=1986|title=Endothelial function|journal=Journal of Critical Care|volume=1|issue=2|page=101 |doi=10.1016/s0883-9441(86)80056-9}}
  • {{cite journal |last1=Ryan|first1=Una|date=December 1987|title=Activation of Endothelial Cells|doi= 10.1111/j.1749-6632.1987.tb33027.x|journal=Annals of the New York Academy of Sciences|volume=516|issue=1|pages=22–38}}
  • {{cite book|last=Ryan|first=Una S.|title=Endothelial Cells|volume=I|date=1988|publisher=CRC Press|location=Boca Raton, Florida|isbn=978-0-849-34988-1}}
  • {{cite book|last=Ryan|first=Una S.|title=Endothelial Cells|volume=II|url=https://books.google.com/books?id=n2jzGYrNfUwC|date=1988|publisher=CRC Press|location=Boca Raton, Florida|isbn=978-0-8493-4991-1}}
  • {{cite book|last=Ryan|first=Una S.|title=Endothelial Cells|volume=III|year=1988|publisher=CRC Press|location=Boca Raton, Florida|isbn=978-0-849-34992-8}}
  • {{cite book|last1=Ryan|first1=Una S.|last2=Rubanyi|first2=Gabor M.|title=Endothelial Regulation of Vascular Tone|url=https://books.google.com/books?id=CN5180BEFEQC|date=November 27, 1991|publisher=Taylor & Francis|location=New York|isbn=978-0-8247-8578-9}}

References

1. ^{{cite web|title=Curriculum Vitae: Una Scully Ryan (formerly Smith)|url=https://industrydocuments.library.ucsf.edu/documentstore/j/l/y/x//jlyx0090/jlyx0090.pdf|publisher=University of California, San Francisco|accessdate=November 12, 2015|location=San Francisco, California|year=1986}}
2. ^{{cite web|last1=Wraith|first1=David|title=Dr Una Scully Ryan|url=http://www.bristol.ac.uk/pace/graduation/honorary-degrees/hondeg09/ryan.html|publisher=University of Bristol|accessdate=November 13, 2015|location=Bristol, England|date=February 18, 2009}}
3. ^{{cite web|title=Author: Una S. Smith|url=https://www.worldcat.org/search?q=au%3Auna+s+smith&fq=ap%3A%22smith+una%22&dblist=638&qt=sort&se=yr&sd=asc&qt=sort_yr_asc|publisher=WorldCat|accessdate=November 13, 2015}}
4. ^{{cite web|title=Una S. Ryan O.B.E., PhD|url=https://www.bloomberg.com/research/stocks/private/person.asp?personId=189372&privcapId=39795862&previousCapId=28877&previousTitle=Genentech,%20Inc.|publisher=Bloomburg Business|accessdate=November 13, 2015|location=New York City|year=2015}}
5. ^{{cite web|title=Author: Una S. Ryan|url=https://www.worldcat.org/search?q=au%3Auna+s+ryan&dblist=638&se=yr&sd=asc&fq=ap%3A%22ryan+una+s%22&qt=facet_ap%3A|publisher=WordCat|accessdate=November 13, 2015}}
6. ^{{cite web|title=Queen of England Honors BOA Member Una S. Ryan|url=http://wi.mit.edu/news/archive/2002/queen-england-honors-boa-member-una-s-ryan|publisher=Whitehead Institute|accessdate=November 13, 2015|location=Cambridge, Massachusetts|date=June 24, 2002}}
7. ^{{cite web|title=Una Ryan|url=http://www.cartierwomensinitiative.com/candidate/una-ryan|publisher=Cartier Women's Initiative Awards|accessdate=November 13, 2015|year=2009}}
8. ^{{cite news|last1=Kirsner|first1=Scott|title=Una Ryan joins non-profit Diagnostics for All as CEO|url=http://www.boston.com/business/technology/innoeco/2009/12/una_ryan_joins_nonprofit_diagn.html|accessdate=November 13, 2015|work=Boston Globe|date=December 9, 2009|location=Boston, Massachusetts}}
9. ^{{cite news|last1=Singer|first1=Emily|title=Una Ryan|url=http://www.technologyreview.com/qa/423729/una-ryan/|accessdate=November 13, 2015|publisher=MIT Technology Review|date=April 19, 2011|location=Cambridge, Massachusetts}}
10. ^{{cite news|last1=Leuty|first1=Ron|title='BioEconomy Initiative' lands biotech exec, investor Una Ryan as chairwoman|url=http://www.bizjournals.com/sanfrancisco/blog/biotech/2013/11/una-ryan-bay-area-bioeconomy-initiative.html|accessdate=November 13, 2015|work=San Francisco Business Times|date=November 11, 2013|location=San Francisco, California}}

Bibliography

  • {{cite book|ref=harv|last=Callow|first=Allan|title=The Man on the Ground: Who Really Wins Our Wars?|url=https://books.google.com/books?id=Ne4OAQAAQBAJ&pg=PR13|date=October 1, 2013|publisher=Authorsolutions|isbn=978-1-4834-0376-2}}

External links

  • [https://www.worldcat.org/search?q=ryan%2C+una+s&dblist=638&se=yr&sd=asc&fq=ap%3A%22ryan+una+s%22&qt=facet_ap%3A WorldCat Publications]
{{Authority control}}{{DEFAULTSORT:Ryan, Una}}

16 : 1941 births|Living people|People from Kuala Lumpur|Malaysian women scientists|Malaysian biologists|Alumni of the University of Bristol|Alumni of the University of Cambridge|University of Miami faculty|Boston University faculty|Women investors|Biotechnologists|Washington University School of Medicine people|Officers of the Order of the British Empire|Albert Einstein World Award of Science Laureates|21st-century women scientists|20th-century women scientists

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