词条 | Weaver Syndrome |
释义 |
The signs of BPDME are first noticed in cattle aged 5–8 months,[3] and include a weaving gait, along with weakness and lack of voluntary coordination of the muscles of the hind limbs (known as ataxia).[2] Signs progressively worsen, and by 18–36 months of age, the animal is unable to rise.[4] Affected animals are euthanized for welfare reasons.[2] References1. ^{{citation |authors=John D. Baird, Ulla M. Sarmiento, Parvathi K. Basrur |title=Bovine Progressive Degenerative Myeloencephalopathy (Weaver Syndrome) in Brown Swiss Cattle in Canada: A Literature Review and Case Report |journal=Canadian Veterinary Journal |year=1988 |volume=29 |number=4 |pages=370–377 |PMID=17423028 |PMC=1680902 }} 2. ^1 2 {{cite journal |last1=Kunz |first1=E |last2=Rothammer |first2=S |last3=Pausch |first3=H |last4=Schwarzenbacher |first4=H |last5=Seefried |first5=FR |last6=Matiasek |first6=K |last7=Seichter |first7=D |last8=Russ |first8=I |last9=Fries |first9=R |last10=Medugorac |first10=I |title=Confirmation of a non-synonymous SNP in PNPLA8 as a candidate causal mutation for Weaver syndrome in Brown Swiss cattle |journal=Genetics, Selection, Evolution|date=18 March 2016 |volume=48 |pages=21 |doi=10.1186/s12711-016-0201-5 |pmid=26992691 |pmc=4797220}} 3. ^{{cite book |last1=Lorenz |first1=Michael D. |last2=Coates |first2=Joan R. |last3=Kent |first3=Marc |title=Handbook of Veterinary Neurology |date=2011 |publisher=Elsevier/Saunders |location=St. Louis, Missouri |isbn=978-1-4377-0651-2 |page=179 |edition=5th}} 4. ^{{cite book |editor1-last=Divers |editor1-first=Thomas J. |editor2-last=Peek |editor2-first=Simon F. |title=Rebhun's Diseases of Dairy cattle |date=2008 |publisher=Saunders Elsevier |location=St. Louis, Missouri |isbn=978-1-4160-3137-6 |edition=2nd |chapter=Degenerative myeloencephalopathy of Brown Swiss Cattle}} 2 : Bovine diseases|Genetic animal diseases |
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