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词条 Anton Köllisch
释义

  1. Life and work

  2. References

  3. Bibliography

Anton Köllisch (16 March 1888 – September 1916) was a German chemist who, whilst working at Darmstadt for pharmaceutical giant Merck, first described the synthesis of the chemical MDMA which would later come to be known as "ecstasy".[1]

Life and work

In 1911, Köllisch published his doctoral dissertation on the topic of indole synthesis from hydrazones under Otto Diels at the University of Berlin.[2][3]

While at Merck, Dr Köllisch was involved in investigating syntheses for methylhydrastinine and hydrastinine. A procedural patent was filed on Christmas Eve 1912 relating to these syntheses, which mentioned MDMA without name as a chemical intermediate.[1]

He was killed in the First World War.

References

1. ^{{Cite journal|last=Freudenmann|first=Roland W.|last2=Oxler|first2=Florian|last3=Bernschneider-Reif|first3=Sabine|date=2006-09-01|title=The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents|journal=Addiction|volume=101|issue=9|pages=1241–1245|doi=10.1111/j.1360-0443.2006.01511.x|issn=0965-2140|pmid=16911722}}
2. ^Köllisch: Zur Kenntnis des Diacetyls. I. Über die Brauchbarkeit der Diacetylphenylhydrazone für Kondensationen. II. Über Versuche zur Ueberführung des Diacetyls in eine Ketotetrose, Inaugural-Dissertation, Berlin: E. Ebering 1911''Hochspringen↑
3. ^{{Cite journal|last=Diels|first=Otto|last2=Köllisch|first2=Anton|date=1911-01-01|title=Zur Kenntnis des Diacetyls: Über die Diacetyl-monophenylhydrazone und ihre Verwendbarkeit für Kondensationen|journal=Berichte der Deutschen Chemischen Gesellschaft|language=en|volume=44|issue=1|pages=263–268|doi=10.1002/cber.19110440140|issn=1099-0682}}

Bibliography

  • Germany, Kaiserliches Patentamt, Patentschrift Nr 274350, http://mdma.net/merck/mdma-patent1.html
  • {{cite journal | pmid = 16397805 | doi=10.1007/s00115-005-2001-y | volume=77 | issue=1 | title=The early history of Ecstasy | date=January 2006 | journal=Nervenarzt | pages=95–6, 98–9 | last1 = Benzenhöfer | first1 = U | last2 = Passie | first2 = T}}
  • Adam, David. [https://www.theguardian.com/drugs/Story/0,,1852855,00.html Truth about ecstasy's unlikely trip from lab to dance floor]: Pharmaceutical company unravels drug's chequered past, Guardian Unlimited, 2006-08-18.
  • {{cite journal | last1 = Freudenmann | first1 = R. W. |display-authors=etal | title = The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents | url = http://www.mdma.net/merck/ecstasy-mdma.pdf | format = PDF | journal = Addiction | volume = 101 | issue = 9| pages = 1241–1245 | doi = 10.1111/j.1360-0443.2006.01511.x | pmid = 16911722 | date=September 2006}}
{{authority control}}{{DEFAULTSORT:Kollisch, Anton}}

4 : 1888 births|German chemists|1916 deaths|German military personnel killed in World War I

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