APFA can refer to:

• Association of Professional Financial Advisers
• American Professional Football Association, now the National Football League
• American Professional Football Association, a name adopted by a short lived American Football League (1938) in 1939
• Association of Professional Flight Attendants, an independent union representing flight attendants at American Airlines
• Australian Professional Footballers' Association
• Association for the Protection of Fur-Bearing Animals
• Australian Powerchair Football Association (Electric wheelchair football/soccer)

• Caproni A21S Calif
• Caproni A P 1
• Caproni AP/1
• Caproni A. P. 1
• Caproni AP 1
• Caproni Bergamaschi AP.1
• Caproni Bergamaschi Ca 135
• Caproni biplane
• Caproni Ca.1
• Caproni Ca 100
• Caproni Ca 101
• Caproni Ca.102
• Caproni Ca. 111
• Caproni Ca.111bis
• Caproni Ca 113
• Caproni Ca.113
• Caproni Ca 113 AQ
• Caproni Ca 114
• Caproni Ca.114
• Caproni Ca.1 (1910)
• Caproni Ca.122
• Caproni Ca.123
• Caproni Ca.132
• Caproni Ca 133
• Caproni Ca 135