词条 | Arctiin |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 457138982 | ImageFile =Arctiin.svg | ImageSize =250 | IUPACName =(3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3- | OtherNames = |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|changed|??}} | CASNo =20362-31-6 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 388452 | PubChem =100528 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 90827 | SMILES = O=C2OC[C@H](Cc1ccc(OC)c(OC)c1)[C@H]2Cc4ccc(O[C@@H]3O[C@@H]([C@@H](O)[C@H](O)[C@H]3O)CO)c(OC)c4 | InChI = 1/C27H34O11/c1-33-18-6-4-14(10-20(18)34-2)8-16-13-36-26(32)17(16)9-15-5-7-19(21(11-15)35-3)37-27-25(31)24(30)23(29)22(12-28)38-27/h4-7,10-11,16-17,22-25,27-31H,8-9,12-13H2,1-3H3/t16-,17+,22+,23+,24-,25+,27+/m0/s1 | InChIKey = XOJVHLIYNSOZOO-SWOBOCGEBY | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C27H34O11/c1-33-18-6-4-14(10-20(18)34-2)8-16-13-36-26(32)17(16)9-15-5-7-19(21(11-15)35-3)37-27-25(31)24(30)23(29)22(12-28)38-27/h4-7,10-11,16-17,22-25,27-31H,8-9,12-13H2,1-3H3/t16-,17+,22+,23+,24-,25+,27+/m0/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = XOJVHLIYNSOZOO-SWOBOCGESA-N | MeSHName =arctigenin |Section2={{Chembox Properties | C=27 | H=34 | O=11 | Appearance = | Density = | MeltingPtC = 110 to 112 | MeltingPt_notes = | BoilingPt = | Solubility = |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} Arctiin is a lignan found in many plants of the Asteraceae family, particularly the greater burdock (Arctium lappa) and Centaurea imperialis, and in Trachelospermum asiaticum, Saussurea heteromalla,[1] and Forsythia viridissima.[2] It is the glucoside of arctigenin. Arctiin and arctigenin have shown anticancer effects in animal research.{{Citation needed|date=December 2015}} They have been found to act as agonists of the adiponectin receptor 1.[3] References1. ^{{cite book |author=Arvind Saklani |author2=Manas Ranjan Sahoo|author3=Prabhu Dutt Mishra|author4=Ram Vishwakarma |title=Indian Journal of Chemistry |publisher=NISCAIR-CSIR |location=India |year=2010 |volume=50B |pages=624 |issn=0975-0983 |url=http://nopr.niscair.res.in/bitstream/123456789/11408/1/IJCB%2050B%284%29%20624-626.pdf}} Retrieved on April 25, 2011. 2. ^{{cite book |author=David J. Triggle |author2=C. R. Ganellin|author3=F. MacDonald |title=Dictionary of Pharmacological Agents |publisher=Chapman & Hall/CRC |location=Boca Raton |year=1996 |volume=1 |pages=172 |isbn=0-412-46630-9 |url=https://books.google.com/books?id=DeX7jgInYFMC&pg=RA1-PA172&dq=arctiin&sig=ACfU3U1eUsRs0h6r9aei25x2WxRiRrqNIA#PRA1-PA172,M1}} Retrieved on September 14, 2008 through Google Book Search. 3. ^{{cite journal | vauthors = Sun Y, Zang Z, Zhong L, Wu M, Su Q, Gao X, Zan W, Lin D, Zhao Y, Zhang Z | title = Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay | journal = PLoS ONE | volume = 8 | issue = 5 | pages = e63354 | year = 2013 | pmid = 23691032 | pmc = 3653934 | doi = 10.1371/journal.pone.0063354 | url = }} External links
4 : Adiponectin receptor agonists|Lignan glucosides|O-Methylated natural phenols|Lactones |
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