“Arogenate dehydrogenase (NAD(P)+)”的意思、由来-开放百科全书

词条

Arogenate dehydrogenase (NAD(P)+)

释义

References

{{Orphan|date=February 2016}}{{enzyme
| Name = Arogenate dehydrogenase (NAD(P)+)
| EC_number = 1.3.1.79
| CAS_number = 64295-75-6
| IUBMB_EC_number = 1/3/1/79
| GO_code =
| image =
| width =
| caption =
}}

In enzymology, an arogenate dehydrogenase [NAD(P)+] ({{EC number|1.3.1.79}}) is an enzyme that catalyzes the chemical reaction

L-arogenate + NAD(P)+ L-tyrosine + NAD(P)H + CO₂

The 3 substrates of this enzyme are L-arogenate, NAD⁺, and NADP⁺, whereas its 4 products are L-tyrosine, NADH, NADPH, and CO₂.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-arogenate:NAD(P)+ oxidoreductase (decarboxylating). Other names in common use include arogenic dehydrogenase (ambiguous), cyclohexadienyl dehydrogenase, and pretyrosine dehydrogenase (ambiguous).

References

{{cite journal |vauthors=Connelly JA, Conn EE |author-link2=Eric Conn | date = 1986 | title = Tyrosine biosynthesis in Sorghum bicolor: isolation and regulatory properties of arogenate dehydrogenase | journal = Z. Naturforsch. C | volume = 41 | pages = 69–78 | pmid = 2939643 | issue = 1–2 }}
{{cite journal |vauthors=Bonner C, Jensen R | date = 1987 | title = Arogenate dehydrogenase | journal = Methods Enzymol. | volume = 142 | pages = 488–94 | pmid = 3600376 | doi = 10.1016/S0076-6879(87)42060-0 | series = Methods in Enzymology | isbn = 978-0-12-182042-8 }}

4 : EC 1.3.1|NADPH-dependent enzymes|NADH-dependent enzymes|Enzymes of unknown structure

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