词条 | Assisted zona hatching |
释义 |
Assisted zona hatching (AZH) is a procedure of assisted reproductive technology in which a small hole is made in the zona pellucida, using a micromanipulator, thereby facilitating for zona hatching to occur.[1][1] Zona hatching is where the blastocyst gets rid of the surrounding zona pellucida to be able to implant in the uterus. EfficacyA systematic review and meta-analysis came to the result that assisted zona hatching is related to increased rates of clinical pregnancy and multiple pregnancy in women with previous repeated failure or frozen-thawed embryos.[2] However, it is unlikely to increase clinical pregnancy rates when performed in fresh embryos transferred to unselected women, to those without poor prognosis or to women of advanced maternal age.[2] Also, overall, there no evidence of a significant difference in live birth rate following assisted hatching compared with no assisted hatching.[3] References1. ^1 IVF-infertility.com {{Assisted reproductive technology}}{{DEFAULTSORT:Assisted Zona Hatching}}{{Human-repro-stub}}2. ^1 {{Cite journal | last1 = Martins | first1 = W. P. | last2 = Rocha | first2 = I. A. | last3 = Ferriani | first3 = R. A. | last4 = Nastri | first4 = C. O. | title = Assisted hatching of human embryos: A systematic review and meta-analysis of randomized controlled trials | doi = 10.1093/humupd/dmr012 | journal = Human Reproduction Update | volume = 17 | issue = 4 | pages = 438–453 | year = 2011 | pmid = 21474527| pmc = }} 3. ^{{Cite journal|last=Farquhar|first=Cindy|last2=Marjoribanks|first2=Jane|date=2018-08-17|title=Assisted reproductive technology: an overview of Cochrane Reviews|journal=Cochrane Database of Systematic Reviews|volume=8|pages=CD010537|doi=10.1002/14651858.cd010537.pub5|issn=1465-1858|pmid=30117155}} 2 : Assisted reproductive technology|Human reproduction |
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