词条 | Auraptene |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 458781721 | ImageFile = Auraptene.png | ImageSize = 250px | IUPACName = 7-((E)-3, 7-Dimethylocta-2, 6-dienyloxy)-2H-chromen-2-one | OtherNames = Aurapten 7-Geranyloxycoumarin |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|changed|??}} | CASNo = 495-02-3 | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 307341 | ChEBI_Ref = {{ebicite|changed|EBI}} | ChEBI = 134355 | PubChem = 1550607 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 1267148 | SMILES = O=C/2Oc1cc(OC\\C=C(/C)CC\\C=C(/C)C)ccc1\\C=C\\2 | InChI = 1/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+ | InChIKey = RSDDHGSKLOSQFK-RVDMUPIBBL | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+ | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = RSDDHGSKLOSQFK-RVDMUPIBSA-N |Section2={{Chembox Properties | C=19 | H=22 | O=3 | MolarMass = 298.376 g/mol | Appearance = | Density = | MeltingPt = | BoilingPt = | Solubility = |Section3={{Chembox Hazards | MainHazards = | FlashPt = | AutoignitionPt = }} Auraptene is a natural bioactive monoterpene coumarin ether. It was first isolated from members of the genus Citrus. Auraptene has shown a remarkable effect in the prevention of degenerative diseases. Many studies have reported the effect of auraptene as a chemopreventative agent against cancers of liver, skin, tongue, esophagus, and colon in rodent models.[1] The effect in humans is not yet known. References1. ^Curini, M., Carvotto, G., Epifano, F. and Giannone, G. "Chemistry and Biological Activity of Natural and Synthetic Prenyloxycoumarins"(2006). Current Medicinal Chemistry, 13, 199-222. {{coumarin}} 3 : Terpeno-phenolic compounds|Coumarins|Ethers |
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