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词条 Auraptene
释义

  1. References

{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 458781721
| ImageFile = Auraptene.png
| ImageSize = 250px
| IUPACName = 7-((E)-3, 7-Dimethylocta-2, 6-dienyloxy)-2H-chromen-2-one
| OtherNames = Aurapten
7-Geranyloxycoumarin
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|changed|??}}
| CASNo = 495-02-3
| ChEMBL_Ref = {{ebicite|correct|EBI}}
| ChEMBL = 307341
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 134355
| PubChem = 1550607
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 1267148
| SMILES = O=C/2Oc1cc(OC\\C=C(/C)CC\\C=C(/C)C)ccc1\\C=C\\2
| InChI = 1/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+
| InChIKey = RSDDHGSKLOSQFK-RVDMUPIBBL
| StdInChI_Ref = {{stdinchicite|correct|chemspider}}
| StdInChI = 1S/C19H22O3/c1-14(2)5-4-6-15(3)11-12-21-17-9-7-16-8-10-19(20)22-18(16)13-17/h5,7-11,13H,4,6,12H2,1-3H3/b15-11+
| StdInChIKey_Ref = {{stdinchicite|correct|chemspider}}
| StdInChIKey = RSDDHGSKLOSQFK-RVDMUPIBSA-N
|Section2={{Chembox Properties
| C=19 | H=22 | O=3
| MolarMass = 298.376 g/mol
| Appearance =
| Density =
| MeltingPt =
| BoilingPt =
| Solubility =
|Section3={{Chembox Hazards
| MainHazards =
| FlashPt =
| AutoignitionPt =
}}

Auraptene is a natural bioactive monoterpene coumarin ether. It was first isolated from members of the genus Citrus.

Auraptene has shown a remarkable effect in the prevention of degenerative diseases. Many studies have reported the effect of auraptene as a chemopreventative agent against cancers of liver, skin, tongue, esophagus, and colon in rodent models.[1] The effect in humans is not yet known.

References

1. ^Curini, M., Carvotto, G., Epifano, F. and Giannone, G. "Chemistry and Biological Activity of Natural and Synthetic Prenyloxycoumarins"(2006). Current Medicinal Chemistry, 13, 199-222.
{{coumarin}}

3 : Terpeno-phenolic compounds|Coumarins|Ethers

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