| 词条 | Autotransplantation |
| 释义 |
Name = Autotransplantation | Image = | Caption = | ICD10 = | ICD9 = | ICD9_mult = | MeshID = D014182 | OPS301 = | OtherCodes = | }} Autotransplantation is the transplantation of organs, tissues, or even particular proteins from one part of the body to another in the same person (auto- meaning "self" in Greek). The autologous tissue (also called autogenous, autogeneic, or autogenic tissue) transplanted by such a procedure is called an autograft or autotransplant. It is contrasted with allotransplantation (from other individual of same species), Syngeneic transplantation (Grafts transplanted between two genetically identical individuals of the same species) and xenotransplantation (from other species). A common example is the removal of a piece of bone (usually from the hip) and its being ground into a paste for the reconstruction of another portion of bone. Autologous blood donation{{see also|Intraoperative blood salvage}}In blood banking terminology, autologous blood donation refers to a blood donation marked for use by the donor, typically for a scheduled surgery. (Generally, the notion of "donation" does not refer to giving to oneself, though in this context it has become somewhat acceptably idiomatic.) They are commonly called "Autos" by blood bank personnel, and it is one major form of the more general concept of autotransfusion (the other being intraoperative blood salvage). Some advantages of autologous blood donation are:
The disadvantages are:
Autologous blood is not routinely tested for infectious diseases markers such as HIV antibodies. In the United States, autologous blood is tested only if it is collected in one place and shipped to another. There is also a risk that, in an emergency or if more blood is required than has been set aside in advance, the patient could still be exposed to donor blood instead of autologous blood. Autologous donation is also not suitable for patients who are medically unable to or advised not to give blood, such as cardiac patients or small children and infants. Bone autograft{{See also|Bone grafting#Autologous bone grafting}}In orthopaedic medicine, bone graft can be sourced from a patient's own bone in order to fill space and produce an osteogenic response in a bone defect. However, due to the donor-site morbidity associated with autograft, other methods such as bone allograft and bone morphogenetic proteins and synthetic graft materials are often used as alternatives. Autografts have long been considered the "Gold Standard" in Oral Surgery and Implant Dentistry because it offered the best regenerations results. Lately, the introduction of morphogen-enhanced bone graft substitutes have shown to show similar success rates and quality of regeneration; however, their price is still very high.{{mcn|date=May 2017}} See also
References1. ^{{cite journal|last=Harlaar|first=JJ|author2=Gosselink, MP|author3= Hop, WC|author4= Lange, JF|author5= Busch, OR|author6= Jeekel, H|title=Blood transfusions and prognosis in colorectal cancer: long-term results of a randomized controlled trial.|journal=Annals of Surgery|date=November 2012|volume=256|issue=5|pages=681–7|pmid=23095610|doi=10.1097/SLA.0b013e318271cedf}} {{Organ transplantation}}{{transfusion medicine}} 3 : Transfusion medicine|Orthopedic surgical procedures|Transplantation medicine |
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