A bayou is a slow-moving stream or a wetland.

Bayou may also refer to:

• Bayou (ballet), a 1952 ballet by George Balanchine
• Bayou (film), a 1957 motion picture directed by Harold Daniels
• Bayou (horse), (1954–1982), an American Thoroughbred racemare
• Bayou (magazine), an American literary magazine
• Bayou Arcana, a 2012 comic anthology
• Bayou Hedge Fund Group, a fraudulent investment scheme
• Bayou Records, a music recording label
• Louiza Bayou (born 1994), Algerian volleyball player
• The Bayou, a music venue and nightclub in Washington, D.C.
• Bayou Country, an album by Creedence Clearwater Revival
• Born on the Bayou, a song by Creedence Clearwater Revival from the album Bayou Country

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