“Benzaldehyde dehydrogenase (NADP+)”的意思、由来-开放百科全书

词条

Benzaldehyde dehydrogenase (NADP+)

释义

References

{{enzyme
| Name = benzaldehyde dehydrogenase (NADP+)
| EC_number = 1.2.1.7
| CAS_number = 9028-89-1
| IUBMB_EC_number = 1/2/1/7
| GO_code = 0018477
| image =
| width =
| caption =
}}

In enzymology, a benzaldehyde dehydrogenase (NADP+) ({{EC number|1.2.1.7}}) is an enzyme that catalyzes the chemical reaction

benzaldehyde + NADP⁺ + H₂O benzoate + NADPH + 2 H⁺

The 3 substrates of this enzyme are benzaldehyde, NADP⁺, and H₂O, whereas its 3 products are benzoate, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the aldehyde or oxo group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is benzaldehyde:NADP+ oxidoreductase. Other names in common use include NADP+-linked benzaldehyde dehydrogenase, and benzaldehyde dehydrogenase (NADP+). This enzyme participates in benzoate degradation via hydroxylation and toluene and xylene degradation.

References

{{cite journal | vauthors = GUNSALUS CF, STANIER RY, Gunsalus IC | author3-link=Irwin Gunsalus | date = 1953 | title = THE ENZYMATIC CONVERSION OF MANDELIC ACID TO BENZOIC ACID III. : Fractionation and Properties of the Soluble Enzymes | journal = J. Bacteriol. | volume = 66 | pages = 548–53 | pmid = 13108854 | issue = 5 | pmc = 317432 }}
{{cite journal | vauthors = Stachow CS, Stevenson IL, Day D | date = 1967 | title = Purification and properties of nicotinamide adenine dinucleotide phosphate-specific benzaldehyde dehydrogenase from Pseudomonas | journal = J. Biol. Chem. | volume = 242 | pages = 5294–300 | pmid = 4383635 | issue = 22 }}

3 : EC 1.2.1|NADPH-dependent enzymes|Enzymes of unknown structure

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