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词条 Blue nevus
释义

  1. Classification

  2. See also

  3. References

  4. External links

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| caption = Micrograph of a blue nevus showing the characteristic pigmented melanocytes between bundles of collagen. H&E stain.
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}}Blue nevus (also known as "blue neuronevus", "dermal melanocytoma", and "nevus bleu"[1]) is a type of melanocytic nevus. The blue colour is caused by the pigment being deeper in the skin than in ordinary nevi. In principle they are harmless[2] but they can sometimes be mimicked by malignant lesions, i.e. some melanomas can look like a blue nevus.[3][4]

Classification

Blue nevi may be divided into the following types:[5]{{rp|701}}

  • A patch blue nevus (also known as an "acquired dermal melanocytosis", and "dermal melanocyte hamartoma") is a cutaneous condition characterized by a diffusely gray-blue area that may have superimposed darker macules.[1]
  • A blue nevus of Jadassohn–Tièche (also known as a "common blue nevus", and "nevus ceruleus") is a cutaneous condition characterized by a steel-blue papule or nodule.[5]{{rp|701}}
  • A cellular blue nevus is a cutaneous condition characterized by large, firm, blue or blue-black nodules.[5]{{rp|701}}
  • An epithelioid blue nevus is a cutaneous condition most commonly seen in patients with the Carney complex.[5]{{rp|701}}
  • A deep penetrating nevus is a type of benign melanocytic skin tumor characterized, as its name suggests, by penetration into the deep dermis and/or subcutis. Smudged chromatic is a typical finding. In some cases mitotic figures or atypical melanocytic cytology are seen, potentially mimicking a malignant melanoma. Evaluation by an expert skin pathologist is advisable in some cases to help differentiate from invasive melanoma.[5]{{rp|701}}
  • An amelanotic blue nevus (also known as a "hypomelanotic blue nevus") is a cutaneous condition characterized by mild atypia and pleomorphism.[5]{{rp|701}}
  • A malignant blue nevus is a cutaneous condition characterized by a sheet-like growth pattern, mitoses, necrosis, and cellular atypia.[1][5]{{rp|701}}

See also

  • List of cutaneous conditions
  • List of genes mutated in pigmented cutaneous lesions

References

1. ^{{cite book |author=Rapini, Ronald P. |author2=Bolognia, Jean L. |author3=Jorizzo, Joseph L. |title=Dermatology: 2-Volume Set |publisher=Mosby |location=St. Louis |year=2007 |pages=1722 |isbn=1-4160-2999-0 |oclc= |doi= |accessdate=}}
2. ^{{cite web |url=http://dermnetnz.org/lesions/blue-naevus.html |title=Blue naevus (nevus). DermNet NZ |work= |accessdate=2009-02-27}}
3. ^{{MeshName|Blue+Nevi}}
4. ^{{cite journal |vauthors=Granter SR, McKee PH, Calonje E, Mihm MC, Busam K |title=Melanoma associated with blue nevus and melanoma mimicking cellular blue nevus: a clinicopathologic study of 10 cases on the spectrum of so-called 'malignant blue nevus' |journal=Am. J. Surg. Pathol. |volume=25 |issue=3 |pages=316–23 |date=March 2001 |pmid=11224601 |doi= 10.1097/00000478-200103000-00005|url=http://meta.wkhealth.com/pt/pt-core/template-journal/lwwgateway/media/landingpage.htm?issn=0147-5185&volume=25&issue=3&spage=316}}
5. ^{{cite book |author=James, William D. |author2=Berger, Timothy G. |title=Andrews' Diseases of the Skin: clinical Dermatology |publisher=Saunders Elsevier |location= |year=2006 |pages= |isbn=0-7216-2921-0 |oclc= |doi= |accessdate=|display-authors=etal}}

External links

{{Medical resources
| DiseasesDB = 31098
| ICD10 = D22 (ILDS D22.L42)
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| MedlinePlus =
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| MeshID = D018329
}}{{Skin tumors, nevi and melanomas}}Naevus caeruleus

1 : Melanocytic nevi and neoplasms

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