词条 | Bronidox |
释义 |
| Watchedfields = changed | verifiedrevid = 462783820 | Name = | ImageFile = Structure of bronidox.png | ImageSize = | ImageName = | IUPACName = 5-Bromo-5-nitro-1,3-dioxane | SystematicName = | OtherNames = 5-Bromo-5-nitro-m-dioxane |Section1={{Chembox Identifiers | Abbreviations = | CASNo = 30007-47-7 | CASNo_Ref = {{cascite|correct|??}} | EINECS = 250-001-7 | EC_number = | UNNumber = | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = | MeSHName = | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = | RTECS = | UNII_Ref = {{fdacite|correct|FDA}} | UNII = U184I9QBNM | Beilstein = | Gmelin = | PubChem = 1807 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 1741 | SMILES = O=[N+]([O-])C1(Br)COCOC1 | InChI = 1/C4H6BrNO4/c5-4(6(7)8)1-9-3-10-2-4/h1-3H2 | InChIKey = XVBRCOKDZVQYAY-UHFFFAOYAG | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C4H6BrNO4/c5-4(6(7)8)1-9-3-10-2-4/h1-3H2 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = XVBRCOKDZVQYAY-UHFFFAOYSA-N | 3DMet = |Section2={{Chembox Properties | C=4 | H=6 | N=1 | O=4 | Br=1 | Appearance = White crystalline powder | Density = | MeltingPtC = 60 | MeltingPt_ref = [1] 58.5−62 °C[2] | MeltingPt_notes = | BoilingPt = | BoilingPt_notes = | Solubility = insoluble | SolubleOther = | Solvent = | LogP = | VaporPressure = | HenryConstant = | AtmosphericOHRateConstant = | pKa = | pKb = |Section3={{Chembox Structure | CrystalStruct = | Coordination = | MolShape = }} |Section4={{Chembox Thermochemistry | DeltaHf = | DeltaHc = | Entropy = | HeatCapacity = }} |Section5={{Chembox Pharmacology | AdminRoutes = | Bioavail = | Metabolism = | HalfLife = | ProteinBound = | Excretion = | Legal_status = | Legal_US = | Legal_UK = | Legal_AU = | Legal_CA = | Pregnancy_category = | Pregnancy_AU = | Pregnancy_US = }} |Section6={{Chembox Explosive | ShockSens = | FrictionSens = | DetonationV = | REFactor = }} |Section7={{Chembox Hazards | ExternalSDS = | EUClass = | MainHazards = Toxic | NFPA-H = | NFPA-F = | NFPA-R = | NFPA-S = | RPhrases = {{R22}} {{R38}} | SPhrases = {{S36}} | RSPhrases = | FlashPt = | AutoignitionPt = | ExploLimits = | LD50 = 590 mg/kg (mouse, oral) 455 mg/kg (rat, oral) 31 mg/kg (rat, ipr.) 2500 µg (mouse, skin) 2500 µg (rat, skin) | PEL = |Section8={{Chembox Related | OtherAnions = | OtherCations = | OtherFunction = | OtherFunction_label = | OtherCompounds = }} Bronidox, or 5-bromo-5-nitro-1,3-dioxane, is an antimicrobial chemical compound. Bronidox causes inhibition of enzyme activity in bacteria.[3] Bronidox is corrosive to metals.[4] Uses
See also
References1. ^5-BROMO-5-NITRO-1,3-DIOXANE {{webarchive|url=https://web.archive.org/web/20160303200521/http://www.chemicalland21.com/lifescience/phar/5-BROMO-5-NITRO-1%2C3-DIOXANE.htm |date=March 3, 2016 }}, chemicalland21.com 2. ^{{cite web|url=http://www.furrental.com/pages/fj/bronidox.pdf |title=Archived copy |accessdate=March 19, 2006 |deadurl=yes |archiveurl=https://web.archive.org/web/20070929124827/http://www.furrental.com/pages/fj/bronidox.pdf |archivedate=September 29, 2007 }} 3. ^{{cite journal |vauthors=Ghannoum M, Thomson M, Bowman W, Al-Khalil S |title=Mode of action of the antimicrobial compound 5-bromo-5-nitro-1,3-dioxane (bronidox) |journal=Folia Microbiol. (Praha) |volume=31 |issue=1 |pages=19–31 |year=1986 |pmid=3082729 |doi=10.1007/BF02928676 }} 4. ^http://www.products.cognis.com/COGNIS/prodleaf.nsf/(SBU_Catalog)/FFAD30C61B67EFEB41256B4100427DD1/$File/BRONIDOX_r_L_5_E.pdf {{dead link|date=April 2016}} 5. ^ {{webarchive |url=https://web.archive.org/web/20041221152225/http://www.totalreproduction.com/products/specs/Bronidox.html |date=December 21, 2004 }} 4 : Organobromides|Dioxanes|Cationic surfactants|Nitro compounds |
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