This cartoon stars Bruce Willis as the voice of an 11-year-old boy who becomes a top spy for a secret espionage organization. The organization, named Globe, contacts Bruno via his computer and a special gadget watch, and are completely unaware of their top spy's young age, as he hides behind a computer simulated avatar of a full grown man (in the image of Bruce Willis).
The members of Globe that Bruno works with in person, such as Jarlesburg (voiced by Tony Jay), and Harris (voiced by Mark Hamill), are unaware that Globe does not know Bruno's actual age, and assume that the organization must know what they are doing sending the boy into dangerous situations.
The episodes consist of Bruno managing to live a double-life without his parents' or friends' knowledge. In one episode, he tells his parents that he is camping in the garden and he sets up a torch to project a fake silhouette of himself onto the side of the tent, so that it looks like he is inside it. Meanwhile, with an alibi set up, Bruno will be out saving the world, or foiling a major heist with the aid of his British spy partner Jarlesburg. In one episode, one of Bruno's classmates caught Bruno on camera in the process of carrying out a spy mission, and tried to blackmail him; however, Bruno erased the video tape and his secret was safe; his classmate was unable to expose him. Later in the series, Jarlesburg quits being Bruno's partner, after hesitating to fire a weapon in fear that he'll hit Bruno. Bruno objects to Jarley quitting the team. Jarley eventually came to his senses and returned to being Bruno's partner. He apologized to Bruno for quitting. In the course of each mission, they usually meet Harris (a spoof of the character "Q" in the James Bond books and films) who supplies Bruno with gadgets which Bruno usually finds a use for later on in the episode. As well as voicing the title character, Willis was one of the executive producers and also co-wrote and sang the theme song for the show with backing singers.
| Nº | Title | Air date{{Episode list | EpisodeNumber = 1 | Title = The Adventure Begins | 1996|9|23}} | ShortSummary = Colonel Muckbar buys the BOOM disk from Lazlo Gigahertz and threatens to blow up the Hoover Dam unless he gets two billion dollars. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 2 | Title = Spies, Lies & Bavarian Pies | 1996|9|30}} | ShortSummary = Von Trapp steals the BOOM disc from Jarlsburg and plans to hold the world hostage. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 3 | Title = North by Southwest | 1996|10|7}} | ShortSummary = Mister X buys stolen Russian warheads and plans to blow up Mount Vicemore at the unveiling ceremony. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 4 | Title = Take Me Out to the Bomb Game | 1996|10|14}} | ShortSummary = Castrato steals a nuclear missile and detonator, and plans to use it unless he receives 50 billion dollars and the New York Yankees. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 5 | Title = High Tide | 1996|10|21}} | ShortSummary = Cy Cologne plans to melt the world's icebergs, which will cause an enormous tidal wave that will destroy half the world. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 6 | Title = Moonbeam & Other Strangers | 1996|10|28}} | ShortSummary = Dr. Moonbeam steals DOGSLED defense weapons and threatens to destroy national landmarks. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 7 | Title = Give Pizza a Chance | 1996|11|4}} | ShortSummary = Lazlo Gigahertz kidnaps several European leaders and uses Bruno to replace them with robots. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 8 | Title = Chip Happens | 1996|11|11}} | ShortSummary = Ramon Ramon shoots down the GLOBE satellite and steals the chip inside, which will enable him to control all electronic communications in the world. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 9 | Title = Mind Over Matter | 1996|11|18}} | ShortSummary = Von Trapp kidnaps Profession Wisensteain, creator of a mind-reading machine, and builds one of his own. He plans to use it on Swiss bankers to get the combinations to their vaults. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 10 | Title = Searching for Booby Vicious | 1996|11|25}} | ShortSummary = Former chess champion Booby Vicious builds a device to take out radar systems. Bruno must win a game of riddles within 24 hours, or he'll destroy the major cities of the world. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 11 | Title = The Fission Mission | 1996|12|2}} | ShortSummary = Mister X kidnaps world leaders, and the ransom is the uranium he needs for his atomic warhead detonator device. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 12 | Title = The A-maze-ing Adventure | 1996|12|9}} | ShortSummary = Lady Di Archer steals a ceremonial scepter so that war between Jumai and Bakare will continue and diamonds can't be mined. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 13 | Title = Jungle Bogey | 1996|12|16}} | ShortSummary = Dr. Benny Butterfinger steals the Thelma – a silent, undetectable plane – and will start bombing world capitals unless he receives three billion dollars. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 14 | Title = Bruno-palooza | 1996|12|23}} | ShortSummary = Armand Geddon steals the explosive Ultra-Blastite, to be triggered by Slather's high notes at the upcoming "Peaceapalooza" concert. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 15 | Title = Fade to Bruno | 1996|12|30}} | ShortSummary = Hollywood director Stuart Pede puts subliminal messages in a movie that will make teenagers kill world leaders and do whatever else he tells them. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 16 | Title = The Spy Just Like Me | 1997|1|6}} | ShortSummary = Von Trapp has built a large "Grosse Gun" and will bombard oil fields unless OPEC gives him all of its oil. He uses a "kinder-spy" of his own to anticipate Bruno's every move. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 17 | Title = Shake, Rattle & Roll | 1997|1|13}} | ShortSummary = Lazlo Gigahertz creates an earthquake-causing machine, with which he plans to destroy the world's largest cities. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 18 | Title = Book 'Em Bruno, Murder One | 1997|1|20}} | ShortSummary = Ho Don Po develops a plastic explosive that allows him to set off dormant volcanoes; the lava flow will turn the ocean property he owns in Hawaii into beachfront property. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 19 | Title = Dr. Nozone | 1997|1|27}} | ShortSummary = Sunblock manufacturer Chick E. Love steals CFCs in order to eliminate the ozone layer and sell more sunblock. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 20 | Title = The Unfriendly Skies | 1997|2|3}} | ShortSummary = Ann T. Mayhem and sons hijack plans and steal their parts to build a superplane. They then threaten to bomb countries unless they receive a ransom. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 21 | Title = My Dogs Are Killin' Me | 1997|2|10}} | ShortSummary = Lazlo Gigahertz gains control over the dogs of the world, and plans to sic them on their masters unless he receives a billion dollars. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 22 | Title = Meteor Showers Bring No Flowers | 1997|2|17}} | ShortSummary = Mad inventor Leonardo Linguini builds a "Cosmic Hole Puncher" which he will use to punch the atmosphere so meteorites can reach the earth's surface. He will destroy every major world capital unless he receives a billion dollars. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 23 | Title = Bye Bye Jarly: Part One | 1997|2|24}} | ShortSummary = The bad guys, with Von Trapp as president, get together to take over the world. Their first step is stealing a new secret radar system. Jarlsburg loses his confidence and retires from GLOBE, leaving Bruno to deal with a new partner. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 24 | Title = Send in the Clones | 1997|3|3}} | ShortSummary = Von Trapp uses DNA samples to create an army of clones of infamous people throughout history, who will help him take over the world. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 25 | Title = Who's There? | 1997|3|10}} | ShortSummary = Dr Nick Knock develops a "Weather Anomalizer" that can alter the weather. He plans to use it to exact his revenge on the scientific community at a reception for Nobel Prize Winners. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 26 | Title = For Your Snake Eyes Only | 1997|3|17}} | ShortSummary = Former Las Vegas magician Snake Eyes kidnaps 12-year-old religious leader Rama Rama, and will sacrifice him, causing mass riots and chaos, unless Rama Rama orders his followers to leave the scared Temple of Paneer. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 27 | Title = Funworld | 1997|3|24}} | ShortSummary = Vorga Lopez plans to overthrow her brother's government in Brazuela. She holds his son hostage at an amusement park, with the entire Brazuelan treasury as ransom. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 28 | Title = Soda Jerk | 1997|3|31}} | ShortSummary = Koos Koos manufactures a soft drink that contains a violence-inducing chemical. He plans to capitalize on arms sales when he starts an unstoppable world war. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 29 | Title = The Last Christmas | 1997|4|7}} | ShortSummary = Mad toy inventor Klaus Von Claus puts computer chips inside a popular type of doll, allowing him to bring them to life. He plans to use them to destroy the world on Christmas Eve at midnight. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 30 | Title = Revenge of the Giganerd | 1997|4|14}} | ShortSummary = Eugene Scuzzybus uses Lazlo Gigahertz's technology to send a hypnotic signal through electrical wiring, making a zombie of anyone who looks at a monitor or TV screen. Lazlo joins Bruno and Jarlsburg on their journey to stop Scuzzybus. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 31 | Title = Bye Bye Jarly: Part Two | 1997|4|21}} | ShortSummary = Continued from Part One. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 32 | Title = Bye Bye Jarly: Part Three | 1997|4|28}} | ShortSummary = Continued from Part Two. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 33 | Title = Bullet Train | 1997|5|5}} | ShortSummary = A man calling himself "The Engineer" takes over a new computerized rail system and threatens to derail every train on the planet. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 34 | Title = Dead Boy Walking | 1997|5|12}} | ShortSummary = Melbourne and Sydney G'Day plan to infect the world with a deadly virus, then sell the antidote and rake in the money. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 35 | Title = Virus | 1997|5|19}} | ShortSummary = Castrato brings down the GLOBE jet, equipped with a computer full of secret GLOBE information. Bruno retrieves the computer, but must take it back so Castrato can download a virus that will erase all the secret information he's learned. | LineColor = FFA500
}}{{Episode list | EpisodeNumber = 36 | Title = You Go, Girl | 1997|5|26}} | ShortSummary = Medusa has a "Molecular Reorganizer" which can turn water into gold and vice versa. She plans to steal the world's supply of gold in order to control the world. Leecy sneaks along on this mission and finds out about Bruno's secret life. | LineColor = FFA500
}} |
Included in the list of additional voices were Frank Welker, Earl Boen, Ed Gilbert and Kenneth Mars.
Episodes were released on tape by Family Home Entertainment, but as of December 2, 2009, there have been no plans for a USA DVD release.
In Italy in 2008, 9 single DVD Volumes were released with 4 episodes per volume with English Soundtrack & English credits, which are now out of print.