| 词条 | Burkholderia thailandensis |
| 释义 |
| color = lightgrey | name = Burkholderia thailandensis | image = Burkholderia thailandensis (3444954404).jpg | image_caption = Burkholderia thailandensis on Ashdown's media | regnum = Bacteria | phylum = Proteobacteria | classis = Betaproteobacteria | ordo = Burkholderiales | familia = Burkholderiaceae | genus = Burkholderia | species = B. thailandensis | binomial = Burkholderia thailandensis | binomial_authority = Brett et al. 1998[1] }}Burkholderia thailandensis is a nonfermenting motile, Gram-negative bacillus that occurs naturally in soil. It is closely related to Burkholderia pseudomallei, but unlike B. pseudomallei, it only rarely causes disease in humans or animals.[2][3][4][5] The lethal inoculum is approximately 1000 times higher than for B. pseudomallei.[6] It is usually distinguished from B. pseudomallei by its ability to assimilate arabinose.[7] Other differences between these species include lipopolysaccharide composition, colony morphology, and differences in metabolism.[8] Use in researchB. thailandensis is sometimes used to model B. pseudomallei infection in mice because of similarities in the immune response.[9][10][11] B. thailandensis does not require biosafety category 3 facilities and is not considered a biosecurity threat, which makes it easier to study and to work with.[12]Small RNAResearch suggests that as in other bacteria, small non coding RNAs play a role in response to the environmental and stress conditions like antibiotic exposure and survival in a host-specific environment.[13] Several small RNA have been discovered in B. thailandenisis: BHT_s1 and BHT_s39 exhibit differential expression profiles dependent on growth phase and cell stimuli, such as antibiotics and serum. BHT_s39 could function in bacterial metabolism and adaptation to host. BTH_s13 and BTH_s19 may regulate expression of their downstream gene.[13] {{See also|Burkholderia cenocepacia}}References1. ^{{cite journal | vauthors=Brett PJ, DeShazer D, Woods DE | title=Burkholderia thailandensis sp. nov., a Burkholderia pseudomallei-like species | journal=Int J Syst Bacteriol | year=1998 | volume=48 | pages=317–320 | pmid=9542103 | doi=10.1099/00207713-48-1-317 }} 2. ^{{cite journal | vauthors=Wuthiekanun V, Smith MD, Dance DA, Walsh AL, Pitt TL, White NJ | title=Biochemical characteristics of clinical and environmental isolates of Burkholderia pseudomallei | journal=J Med Microbiol | year=1996 | volume=45 | issue=6 | pages=408–12 | pmid=8958243 | doi=10.1099/00222615-45-6-408 }} 3. ^{{cite journal | vauthors=Smith MD, Angus BJ, Wuthiekanun V, White NJ | title=Arabinose assimilation defines a nonvirulent biotype of Burkholderia pseudomallei | journal=Infect Immun | year=1997 | volume=65 | issue=10 | pages=4319–21 | pmid=9317042 | pmc=175618 }} 4. ^{{cite journal|vauthors=Lertpatanasuwan N, Sermsri K, Petkaseam A, Trakulsomboon S, Thamlikitkul V, Suputtamongkol Y|title=Arabinose-positive Burkholderia pseudomallei infection in humans: case report|journal=Clin Infect Dis|year=1999|volume=28|pages=927–28|doi=10.1086/517253|pmid=10825075|issue=4}} 5. ^{{cite journal|vauthors=Glass MB, Gee JE, Steigerwalt AG|title=Pneumonia and Septicemia Caused by Burkholderia thailandensis in the United States|journal=J Clin Microbiol|year=2006|volume=44|pages=4601–04|doi=10.1128/JCM.01585-06|pmid=17050819|issue=12|pmc=1698378|display-authors=etal}} 6. ^{{cite journal|vauthors=Wiersinga WJ, de Vos AF, de Beer R|title=Inflammation patterns induced by different Burkholderia species in mice|journal=Cell Microbiol|year=2007|volume=10|issue=1|pages=81–87|doi=10.1111/j.1462-5822.2007.01016.x|pmid=17645551|display-authors=etal}} 7. ^{{cite journal|vauthors=Smith MD, Angus BJ, Wuthiekanun V, White NJ|title=Arabinose assimilation defines a nonvirulent biotype of Burkholderia pseudomallei|journal=Infect Immun|year=1997|volume=65|pages=4319–321|pmid=9317042|issue=10|pmc=175618}} 8. ^{{cite journal | author=Woods DE | title=Species versus Biotype Status | journal=J Clin Microbiol | year=1999 | volume=37 | issue=11 | pages=3786–7 | pmid=10610379 | pmc=85768 }} 9. ^{{cite journal|vauthors=Wiersinga WJ, de Vos AF, de Beer R, Wieland CW, ((Roelofs JJTH)), Woods DE|title=Inflammation patterns induced by different Burkholderia species in mice|journal=Cell Microbiol|year=2008|volume=10|pages=81–7|doi=10.1111/j.1462-5822.2007.01016.x|pmid=17645551|issue=1}} 10. ^{{cite journal|vauthors=Haraga A, West TE, Brittnacher MJ, Skerrett SJ, Miller SI|title=Burkholderia thailandensis as a model system for the Study of the virulence-associated type III secretion system of Burkholderia pseudomallei|journal=Infect Immun|year=2008|volume=76|issue=11|pages=5402–11|doi=10.1128/IAI.00626-08|pmid=18779342|pmc=2573339}} 11. ^{{cite journal|vauthors=Morici LA, Heang J, Tate T, Didier PJ, Roy CJ|title=Differential susceptibility of inbred mouse strains to Burkholderia thailandensis aerosol infection|journal=Microb Pathog|year=2010|volume=48|issue=1|pages=9–17|pmid=19853031|doi=10.1016/j.micpath.2009.10.004}} 12. ^{{cite journal|vauthors=Haraga A, West TE, Brittnacher MJ, Skerrett SJ, Miller SI|title=Burkholderia thailandensis as a Model System for the Study of the Virulence-Associated Type III Secretion System of Burkholderia pseudomallei|journal=Infect Immun|year=2008|volume=76|issue=11|pages=5402–11|pmid=18779342|doi=10.1128/IAI.00626-08|pmc=2573339}} 13. ^1 {{Cite journal|last=Stubben|first=Chris J.|last2=Micheva-Viteva|first2=Sofiya N.|last3=Shou|first3=Yulin|last4=Buddenborg|first4=Sarah K.|last5=Dunbar|first5=John M.|last6=Hong-Geller|first6=Elizabeth|date=2014-05-19|title=Differential expression of small RNAs from Burkholderia thailandensis in response to varying environmental and stress conditions|journal=BMC Genomics|volume=15|pages=385|doi=10.1186/1471-2164-15-385|issn=1471-2164|pmc=4035088|pmid=24884623}} External links
2 : Burkholderiales|Bacteria described in 1998 |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。