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词条 Cardiovascular physiology
释义

  1. Heart

  2. Regulation of blood pressure

     Hemodynamics 

  3. Regional circulation

  4. See also

  5. References

  6. External links

Cardiovascular physiology is the study of the cardiovascular system, specifically addressing the physiology of the heart ("cardio") and blood vessels ("vascular").

These subjects are sometimes addressed separately, under the names cardiac physiology and circulatory physiology.[1]

Although the different aspects of cardiovascular physiology are closely interrelated, the subject is still usually divided into several subtopics.

Heart

{{Main|Cardiac physiology}}
  • Cardiac output (= heart rate stroke volume. Can also be calculated with Fick principle.)
    • Stroke volume (= end-diastolic volume − end-systolic volume)
    • Ejection fraction (= stroke volume / end-diastolic volume)
    • Cardiac output is mathematically ` to systole{{Clarify|date=February 2018}}
    • Inotropic, chronotropic, and dromotropic states
    • Cardiac input (= heart rate suction volume Can be calculated by inverting terms in Fick principle)
    • Suction volume (= end-systolic volume + end-diastolic volume)
    • Injection fraction (=suction volume / end-systolic volume)
    • Cardiac input is mathematically ` to diastole{{Clarify|date=February 2018}}
  • Electrical conduction system of the heart
    • Electrocardiogram
    • Cardiac marker
    • Cardiac action potential
  • Frank–Starling law of the heart
  • Wiggers diagram
  • Pressure volume diagram

Regulation of blood pressure

  • Baroreceptor
  • Baroreflex
  • Renin–angiotensin system
    • Renin
    • Angiotensin
  • Juxtaglomerular apparatus
  • Aortic body and carotid body
  • Autoregulation
    • Cerebral Autoregulation

Hemodynamics

Under most circumstances, the body attempts to maintain a steady mean arterial pressure.

When there is a major and immediate decrease (such as that due to hemorrhage or standing up), the body can increase the following:

  • Heart
  • Total peripheral resistance (primarily due to vasoconstriction of arteries)
  • Inotropic state

In turn, this can have a significant impact upon several other variables:

  • Stroke volume
  • Cardiac output
  • Pressure
    • Pulse pressure (systolic pressure - diastolic pressure)
    • Mean arterial pressure (usually approximated with diastolic pressure + 1/3 pulse pressure)
    • Central venous pressure

Regional circulation

Name of circulation % of cardiac output Autoregulation Perfusion Comments
pulmonary circulation 100% (deoxygenated) Vasoconstriction in response to hypoxia
cerebral circulation 15%[2] high under-perfused Fixed volume means intolerance of high pressure. Minimal ability to use anaerobic respiration
coronary circulation 5% high under-perfused Minimal ability to use anaerobic respiration. Blood flow through the left coronary artery is at a maximum during diastole (in contrast to the rest of systemic circulation, which has a maximum blood flow during systole.)
splanchnic circulation 15% low Flow increases during digestion.
hepatic circulation 15% Part of portal venous system, so oncotic pressure is very low
renal circulation 25% high over-perfused Maintains glomerular filtration rate
skeletal muscular circulation 17%[3] Perfusion increases dramatically during exercise.
cutaneous circulation 2%[4] over-perfused Crucial in thermoregulation. Significant ability to use anaerobic respiration

See also

  • Cardiovascular System Dynamics Society

References

1. ^Overview {{webarchive |url=https://web.archive.org/web/20070117015138/http://www.lib.mcg.edu/edu/eshuphysio/program/section3/3outline.htm |date=January 17, 2007 }} at Medical College of Georgia
2. ^{{GeorgiaPhysiology|3/3ch11/s3c11_13}}
3. ^{{GeorgiaPhysiology|3/3ch11/s3c11_2}}
4. ^{{GeorgiaPhysiology|3/3ch11/s3c11_10}}

External links

  • {{MeshName|Cardiovascular+physiology}}
  • Cardiovascular Physiology Concepts - Comprehensive explanation of basic cardiovascular concepts, based on a textbook of the same name.
  • The Gross Physiology of the Cardiovascular System - Mechanical overview of cardiovascular function. Free eBook and video resources.
  • [https://itunes.apple.com/gb/app/clinical-sciences-cardiovascular/id465102656?mt=8 Clinical Sciences - Cardiovascular] An iPhone app covering detailed cardiovascular physiology and anatomy
  • Quantitative Cardiovascular Physiology and Clinical Applications for Engineers
{{Cardiovascular physiology}}

5 : Cardiovascular physiology|Cardiology|Circulatory system|Heart|Cardiac anatomy

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