CFIX may refer to:

• CFIX-FM, a radio station (96.9 FM) licensed to Saguenay, Quebec, Canada
• CFIX (AM), a defunct radio station (1170 AM) formerly licensed to Cornwall, Ontario, Canada
• Cefixime, by the trade name CFIX

• Grand Challenges (disambiguation)
• Grand Challenges for Social Work
• Grand Champeen
• Grandchamp House
• Grand chancelier
• Grand Chancellor of China
• Grand chess
• Grand Chessboard
• Grand Chess Tour
• Grand Chief (Mi'kmaq people)
• Grand Chiffre
• Grandchildren of Queen Victoria and Albert of Saxe-Coburg and Gotha
• Grandchildren of Victoria and Albert
• Grand chord
• Grand/Cicero (Metra station)
• Grand/Cicero station (Illinois)
• Grand/Cicero station (Metra)
• Grand Cinema (Shanghai)
• Grand Cipher
• Grand Circuit
• Grand Circus Park Station
• Grand Circus Park station (Detroit)
• Grand Clocher du Portalet
• Grand coalition (Austria)
• Grand coalition (Iran)