Charles Stein may refer to:

• Charles Stein (athlete) (1911-1981), Luxembourgian Olympic runner
• Charles Stein (statistician) (1920-2016), American statistician
• Charles F. Stein (1900–1979), Baltimore historian and heraldist
• Charles Francis Stein, Sr. (1866–1939), Baltimore city judge
• Charles Ramsay Stirling Stein (1897–?), Canadian Army officer
• Charles-Adolphe Stein (1878–1938), Quebec politician, lawyer and judge

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