| 词条 | Cheryl Arrowsmith |
| 释义 |
| honorific_prefix = | name = | honorific_suffix = | native_name = | native_name_lang = | image = | image_size = | image_upright = | alt = | caption = | birth_name = | birth_date = | birth_place = | death_date = | death_place = | death_cause = | resting_place = | resting_place_coordinates = | home_town = | other_names = | pronounce = | residence = | citizenship = | nationality = Canadian | fields = Structural biology | workplaces = Structural Genomics Consortium | patrons = | education = | alma_mater = University of Toronto | thesis_title = | thesis_url = | thesis_year = | doctoral_advisor = | academic_advisors = | doctoral_students = | notable_students = | known_for = | influences = | influenced = | awards = | author_abbrev_bot = | author_abbrev_zoo = | spouse = | partner = | children = | signature = | signature_alt = | website = | footnotes = }} Cheryl H. Arrowsmith is a Canadian structural biologist and is the Chief Scientist at the Toronto laboratory of the Structural Genomics Consortium. Her contributions to protein structural biology[1] includes the use of NMR and X-ray crystallography to pursue structures of proteins on a proteome wide scale. She received her Ph.D. in chemistry at the University of Toronto in 1987 and post-doctoral training at Stanford University working with Oleg Jardetzky. One of her areas of interest is the tumour suppressor p53 and related proteins.[2] Her current research is to determine the 3-dimensional structures of human proteins of therapeutic relevance by structural proteomics.[3] She made significant contributions to epigenetic signaling with her highest cited paper is "Epigenetic protein families: a new frontier for drug discovery"[4] cited at 802 times, according to Google Scholar.[5] Arrowsmith was named a Fellow of the American Association for the Advancement of Science (AAAS) in 2015.[6] References1. ^{{Cite web |url=http://www.uhnresearch.ca/researchers/profile.php?lookup=210 |title=Cheryl H. Arrowsmith |publisher=uhnresearch.ca |accessdate=December 27, 2017}} {{authority control}}{{DEFAULTSORT:Arrowsmith, Cheryl}}{{Canada-scientist-stub}}2. ^{{Cite web |url=http://nmr.uhnres.utoronto.ca/arrowsmith/ |title=Cheryl Arrowsmith |publisher=utoronto.ca |accessdate=December 27, 2017}} 3. ^{{cite journal |author=Chandonia JM, Brenner SE |title=The impact of structural genomics: expectations and outcomes |journal=Science |volume=311 |issue=5759 |pages=347–51 |date=January 2006 |pmid=16424331 |doi=10.1126/science.1121018 |url=http://www.sciencemag.org/cgi/content/abstract/311/5759/347}} 4. ^Cheryl H. Arrowsmith, Chas Bountra, Paul V. Fish, Kevin Lee & Matthieu Schapira. Epigenetic protein families: a new frontier for drug discovery. Nature Reviews Drug Discovery 11, 384–400 (2012) 5. ^{{Cite web |url=https://scholar.google.com/scholar?hl=en&as_sdt=0%2C44&q=Cheryl+Arrowsmith&btnG= |title=Cheryl Arrowsmith |publisher=scholar.google.com |accessdate=December 27, 2017}} 6. ^{{Cite web |url=http://medicine.utoronto.ca/news/arrowsmith-named-aaas-fellow |title=Arrowsmith named AAAS Fellow |publisher=utoronto.ca |accessdate=December 27, 2017}} 18 : Living people|University of Toronto alumni|Canadian company founders|Technology company founders|Canadian women company founders|Structural biologists|Canadian geneticists|Canadian biochemists|Women biochemists|Women geneticists|Canadian women biologists|Canadian women chemists|21st-century women scientists|21st-century biologists|21st-century chemists|Year of birth missing (living people)|Place of birth missing (living people)|Fellows of the American Association for the Advancement of Science |
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