| 词条 | Chloral hydrate/magnesium sulfate/pentobarbital |
| 释义 |
| drug_name = | type = combo | component1 = Chloral hydrate | class1 = Sedative | component2 = Magnesium sulfate | class2 = Neuromuscular blocker | component3 = Pentobarbital | class3 = Barbiturate | pronounce = | tradename = Equithesin | pregnancy_category= | legal_status = | routes_of_administration = }} Chloral hydrate/magnesium sulfate/pentobarbital sodium, brand name Equithesin, is a combination anesthetic agent used as a general anesthetic in horses.[1] It is administered intravenously to effect. For many years, it was the most commonly used injectable anesthetic in horses. Newer anesthetic agents such as injectable barbiturates, alpha-2 agonists, cyclohexylamines, and inhalants gradually replaced Equithesin. The drug has been off the market and unavailable for decades.{{Citation needed|date=November 2008}} This combination anesthetic agent contains 42.5 mg chloral hydrate, 21.2 mg magnesium sulfate and 8.86 mg pentobarbital per milliliter.[2] References1. ^{{cite book |editor1-last=Studdert |editor1-first=Virginia P. |editor2-last=Gay |editor2-first=Clive C. |editor3-last=Blood |editor3-first=Douglas C. |title=Saunders comprehensive veterinary dictionary |date=2012 |publisher=Elsevier Saunders |location=Edinburgh |isbn=9780702047442 |page=393 |edition=4th |chapter=Equithesin}} {{Anesthetics}}{{GABAAR PAMs}}{{Glutamatergics}}{{nervous-system-drug-stub}}2. ^{{cite book |last1=Posner |first1=Lysa P. |last2=Burns |first2=Patrick |editor1-last=Riviere |editor1-first=Jim E. |editor2-last=Papich |editor2-first=Mark G. |title=Veterinary pharmacology and therapeutics. |date=2009 |publisher=Wiley-Blackwell |location=Ames, Iowa |isbn=978-0-8138-2061-3 |page=291–292 |edition=9th |chapter=Chapter 11. Injectable anesthetic agents. Miscellaneous intravenous anesthetics}} 4 : General anesthetics|GABAA receptor positive allosteric modulators|Veterinary drugs|Combination drugs |
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