| 词条 | Chris Abell |
| 释义 |
| name = | honorific_suffix = {{post-nominals|country=GBR|FRS|FRSC|FMedSci|size=100%}} | native_name = | native_name_lang = | image = Professor_Christopher_Abell_FMedSci_FRS.jpg | image_size = | alt = | caption = Chris Abell at the Royal Society admissions day in London, July 2016 | birth_date = {{birth date and age|df=yes|1957|11|11}} | birth_name = Christopher Abell | birth_place = | death_date = | death_place = | death_cause = | resting_place = | resting_place_coordinates = | other_names = | residence = | citizenship = | nationality = British | fields = Biological chemistry | workplaces = University of Cambridge Brown University | patrons = | education = University of Cambridge (BA, MA, PhD) | thesis_title = Polyketide biosynthesis | thesis_url = http://ethos.bl.uk/OrderDetails.do?uin=uk.bl.ethos.350039 | thesis_year = 1982 | doctoral_advisor = James Staunton | academic_advisors = | doctoral_students = Shankar Balasubramanian[1] | notable_students = | known_for = Astex[2] biosynthesis as targets for the rational design of antimicrobials; fragment-based approaches to enzyme inhibition; and biological nanotechnology | influences = | influenced = | awards = Hickinbottom Award (1991){{citation needed|date=March 2018}} | spouse = | partner = | children = | signature = | signature_alt = | website = {{URL|www.ch.cam.ac.uk/person/ca26}} | footnotes = }}Christopher Abell {{post-nominals|country=GBR|FRS|FRSC|FMedSci}}[3] (born 11 November 1957)[4] is a British biological chemist. As of 2016, he is Professor of Biological Chemistry at the Department of Chemistry of the University of Cambridge and Todd-Hamied Fellow of Christ's College, Cambridge.[5] On his 2016 election to the Royal Society, the society described his research as having "changed the face of drug discovery."[6] EducationAbell was educated at St John's College, Cambridge,[4] gaining an Bachelor of Arts degree in Natural Sciences in 1979 followed by PhD[7] on the topic of polyketide biosynthesis for research supervised by James Staunton in 1982.[8] Career and researchAbell held a research fellowship in the laboratory of David E. Cane at Brown University, Providence, USA, studying terpene biosynthesis (1982–83).[4][8] In 1984, Abell joined the Department of Chemistry of the University of Cambridge, successively holding the positions of demonstrator, lecturer and reader in chemical biology, and becoming Professor in Biological Chemistry in 2002.[4][8] He has held visiting professorships at the Australian National University in Canberra, University of Santiago de Compostela, University of Canterbury, Christchurch, and the Paul Sabatier University, Toulouse.[4][8][9] He has been a fellow of Christ's College, Cambridge since 1986;{{citation needed|date=March 2018}} and is the college's Todd-Hamied Fellow.[10] In 2013 he was appointed the first Director of Postdoctoral Affairs at the University of Cambridge,[11] and in 2016 was appointed Pro-Vice-Chancellor for Research. Abell has published over 200 papers.[4] His research interests include vitamin and amino acid biosynthesis as targets for the rational design of antimicrobials; fragment-based approaches to enzyme inhibition; bacterial and plant riboswitches; reactions in microdroplets;[12] and biological nanotechnology.[13] His former doctoral students include Shankar Balasubramanian.[1] Commercial venturesAbell is the co-founder of several companies. In 1999, he co-founded Astex Technology Ltd, which uses fragment-based drug discovery technology to discover cancer therapeutics.[4][9] In 2001, he co-founded Akubio, which developed biosensors for detecting bacteria and viruses; it was acquired by Inverness Medical Innovations in 2008.[14] In 2010, he co-founded Sphere Fluidics to develop microdroplet technology.[15] In 2012 he co-founded Aqdot, a company developing a new microencapsulation technology.{{citation needed|date=November 2013}} Publications{{div col|colwidth=35em}}
Awards and honoursHis awards include a Research Fellowship at King's College, Cambridge,{{when|date=March 2018}} the Imperial Chemical Industries (ICI) Prize in Organic Chemistry in 1992,{{citation needed|date=March 2018}} the Hickinbottom Award of the Royal Society of Chemistry,{{citation needed|date=March 2018}} and a Yamada Science Foundation Award.[4][8] In 2008 he was the MIT Novartis Lecturer, and in 2011 was a BIC International Fellow at the University of Canterbury, Christchurch, New Zealand.[16] He was elected a Fellow of the Academy of Medical Sciences (FMedSci) in 2012[17] and a Fellow of the Royal Society (FRS) in 2016.[18] References1. ^1 {{cite thesis |degree=PhD |first=Shankar|last=Balasubramanian |title=Studies on the reaction mechanism of chorismate synthase |publisher=University of Cambridge |date=1991 |url=http://ulmss-newton.lib.cam.ac.uk/vwebv/holdingsInfo?bibId=5839|oclc=60112382|id={{EThOS|uk.bl.ethos.386780}}|website=lib.cam.ac.uk}} {{Authority control}}{{FRS 2016}}{{DEFAULTSORT:Abell, Chris}}2. ^{{cite web|url=https://beta.companieshouse.gov.uk/officers/CIo3M8HOO-_8UJrzWmT7eyT4_KQ/appointments|title=Christopher ABELL - Personal Appointments (free information from Companies House)|website=beta.companieshouse.gov.uk}} 3. ^{{cite news |page=57 |date=27 October 2015 |title=Fellows (FRSC) |newspaper=The Times }} 4. ^1 2 3 4 5 6 7 Abell, Prof Christopher. In Debrett's People of Today 2012 (accessed 15 January 2012) (subscription required) 5. ^{{cite web|url=https://web.archive.org/web/20130407084006/http://astx.com/about/scientific_advisory_board/|title=Scientific Advisory Board|date=7 April 2013|publisher=}} 6. ^{{citation |url=https://royalsociety.org/news/2016/04/new-fellows-2016/ |title=50 leading scientists elected as Fellows of Royal Society |date=29 April 2016 |accessdate=2 September 2016 }} 7. ^{{cite thesis|degree=PhD|publisher=University of Cambridge|url=http://idiscover.lib.cam.ac.uk/primo-explore/fulldisplay?docid=44CAM_ALMA21428181990003606&context=L&vid=44CAM_PROD&search_scope=SCOP_CAM_ALL&tab=cam_lib_coll&lang=en_US|doi=|title=Polyketide biosynthesis|first= Christopher|last=Abell|date=1982|id={{EThOS|uk.bl.ethos.350039}}|website=lib.cam.ac.uk|oclc=59312458|hdl=}} 8. ^1 2 3 4 {{webarchive |url=https://web.archive.org/web/20060925145219/http://www-abell.ch.cam.ac.uk/abellgroup/cv/cv.html |date=25 September 2006 |title=Abell Group Home Page: Curriculum vitae: Professor Christopher Abell }} (accessed 15 January 2013) 9. ^1 Astex Therapeutics: Scientific Advisors and Clinical Consultants (accessed 5 January 2009) 10. ^Christ's College, University of Cambridge: The Fellows of Christ's College {{webarchive |url=https://web.archive.org/web/20130305100653/http://www.christs.cam.ac.uk/college-life/people/fellows/ |date=5 March 2013 }} (accessed 7 January 2013) 11. ^University of Cambridge: New senior post to support post-doc community (accessed 28 November 2013) 12. ^1 {{cite journal|last1=Theberge|first1=Ashleigh B.|last2=Courtois|first2=Fabienne|last3=Schaerli|first3=Yolanda|last4=Fischlechner|first4=Martin|last5=Abell|first5=Chris|last6=Hollfelder|first6=Florian|last7=Huck|first7=Wilhelm T. S.|title=Microdroplets in Microfluidics: An Evolving Platform for Discoveries in Chemistry and Biology|journal=Angewandte Chemie International Edition|volume=49|issue=34|year=2010|pages=5846–5868|issn=1433-7851|doi=10.1002/anie.200906653|pmid= 18264960}} 13. ^University of Cambridge: Department of Chemistry: Professor Chris Abell (accessed 5 January 2009) 14. ^Vargas L. Recycled Cambridge biosensor technology attracts millions in investment Business Weekly (27 August 2008) (accessed 5 January 2009) 15. ^Sphere Fluidics: 2010 News {{webarchive |url=https://web.archive.org/web/20121118084242/http://www.spherefluidics.com/news_2010.php |date=18 November 2012 }} (accessed 7 January 2013) 16. ^International Fellows, University of Canterbury – Christchurch. Retrieved 3 December 2013 17. ^The Academy of Medical Sciences: Fellows: Newly elected fellows (accessed 7 January 2013) 18. ^{{cite web|url= https://royalsociety.org/people/christopher-abell-12842/|title= Professor Christopher Abell Biography|publisher= Royal Society|accessdate= 1 May 2016}} 9 : 1957 births|Living people|British chemists|Fellows of the Academy of Medical Sciences|Members of the University of Cambridge Department of Chemistry|Fellows of Christ's College, Cambridge|Alumni of St John's College, Cambridge|Fellows of the Royal Society of Chemistry|Fellows of the Royal Society |
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