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词条 Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
释义

  1. References

{{enzyme
| Name = cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase
| EC_number = 1.3.1.56
| CAS_number =
| IUBMB_EC_number = 1/3/1/56
| GO_code = 0018509
| image =
| width =
| caption =
}}

In enzymology, a cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase ({{EC number|1.3.1.56}}) is an enzyme that catalyzes the chemical reaction

cis-3-phenylcyclohexa-3,5-diene-1,2-diol + NAD+ biphenyl-2,3-diol + NADH + H+

Thus, the two substrates of this enzyme are cis-3-phenylcyclohexa-3,5-diene-1,2-diol and NAD+, whereas its 3 products are biphenyl-2,3-diol, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is cis-3-phenylcyclohexa-3,5-diene-1,2-diol:NAD+ oxidoreductase. This enzyme is also called 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase. This enzyme participates in biphenyl degradation.

References

  • {{cite journal | vauthors = Sylvestre M, Hurtubise Y, Barriault D, Bergeron J, Ahmad D | date = 1996 | title = Characterization of active recombinant 2,3-dihydro-2,3-dihydroxybiphenyl dehydrogenase from Comamonas testosteroni B-356 and sequence of the encoding gene (bphB) | journal = Appl. Environ. Microbiol. | volume = 62 | pages = 2710–5 | pmid = 8702262 | issue = 8 | pmc = 168055 }}
  • {{cite journal | vauthors = Takagi M, Yano K | date = 1994 | title = Identification of the bphA and bphB genes of Pseudomonas sp. strains KKS102 involved in degradation of biphenyl and polychlorinated biphenyls | journal = Biochem. Biophys. Res. Commun. | volume = 202 | pages = 850–6 | pmid = 8048958 | doi = 10.1006/bbrc.1994.2008 | issue = 2 }}
  • {{cite journal | vauthors = Hofer B, Eltis LD, Dowling DN, Timmis KN | date = 1993 | title = Genetic analysis of a Pseudomonas locus encoding a pathway for biphenyl/polychlorinated biphenyl degradation | journal = Gene | volume = 130 | pages = 47–55 | pmid = 8344527 | doi = 10.1016/0378-1119(93)90345-4 | issue = 1 }}
{{CH-CH oxidoreductases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{1.3-enzyme-stub}}

3 : EC 1.3.1|NADH-dependent enzymes|Enzymes of unknown structure

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