词条 | Clonally transmissible cancer |
释义 |
A transmissible cancer is a cancer cell or cluster of cancer cells that can be transferred between individuals without the involvement of an infectious agent, such as an oncovirus.[1][2] Transmission of cancer between humans is rare.[2] Contagious cancers are known to occur in dogs, Tasmanian devils, Syrian hamsters, and some marine bivalves including soft-shell clams. These cancers have a relatively stable genome as they are transmitted.[3] In humans, a significant fraction of Kaposi's sarcoma occurring after transplantation may be due to tumorous outgrowth of donor cells.[4] Although Kaposi's sarcoma is caused by a virus (Kaposi's sarcoma-associated herpesvirus), in these cases, it appears likely that transmission of virus-infected tumor cells—rather than the free virus—caused tumors in the transplant recipients.[2] Notable cases
Other animalsClonally transmissible cancer, caused by a clone of malignant cells rather than a virus,[8] is an extremely rare disease modality,[9] with few transmissible cancers being known[1] Animals that have undergone population bottlenecks may be at greater risks of contracting transmissible cancers.[10] Because of their transmission, it was initially thought that these diseases were caused by the transfer of oncoviruses, in the manner of cervical cancer caused by HPV.[2] However, canine transmissible venereal tumor mutes the expression of the immune response, whereas the Syrian hamster disease spreads due to lack of genetic diversity.[11]
See also
References1. ^1 {{Cite journal|last=Ostrander|first=Elaine A.|last2=Davis|first2=Brian W.|last3=Ostrander|first3=Gary K.|date=January 2016|title=Transmissible Tumors: Breaking the Cancer Paradigm|journal=Trends in Genetics|volume=32|issue=1|pages=1–15|doi=10.1016/j.tig.2015.10.001|issn=0168-9525|pmc=4698198|pmid=26686413}} 2. ^1 2 3 {{cite journal | last = Welsh | first = James S. |title=Contagious cancer |journal=The Oncologist |volume=16 |issue=1 |pages=1–4 |year=2011 |pmid=21212437 |doi=10.1634/theoncologist.2010-0301 |pmc=3228048}} 3. ^{{cite journal | url = http://www.retrovirology.com/content/3/S1/S92 | journal = Retrovirology | title = A sexually transmitted parasitic cancer | date = 21 December 2006 | volume = 3 | issue = Supplement 1 | page = S92 | doi = 10.1186/1742-4690-3-S1-S92 | first1 = Robin A. | last1 = Weiss | first2 = Ariberto | last2 = Fassati | first3 = Claudio | last3 = Murgia }} 4. ^{{Cite journal | last1 = Barozzi | first1 = Patrizia | last2 = Luppi | first2 = Mario | last3 = Facchetti | first3 = Fabio | last4 = Mecucci | first4 = Cristina | last5 = Alù | first5 = Milena | last6 = Sarid | first6 = Ronit | last7 = Rasini | first7 = Valeria | last8 = Ravazzini | first8 = Luisa | last9 = Rossi | first9 = Elisa | last10 = Festa | first10 = Silvana | last11 = Crescenzi | first11 = Barbara | last12 = Wolf | first12 = Dana G. | last13 = Schulz | first13 = Thomas F. | last14 = Torelli | first14 = Giuseppe | title = Post-transplant Kaposi sarcoma originates from the seeding of donor-derived progenitors | doi = 10.1038/nm862 | journal = Nature Medicine | volume = 9 | issue = 5 | pages = 554–561 | year = 2003 | pmid = 12692543 }} 5. ^{{Cite journal|last=Matser|first=Y|last2=Terpstra|first2=M|last3=Nadalin|first3=S|last4=Nossent|first4=G|last5=de Boer|first5=J|last6=van Bemmel|first6=B|last7=van Eeden|first7=S|last8=Budde|first8=K|last9=Brakemeier|first9=S|date=2018-04-27|title=Transmission of breast cancer by a single multiorgan donor to 4 transplant recipients|journal=American Journal of Transplantation|volume=18|issue=7|pages=1810–1814|doi=10.1111/ajt.14766|pmid=29633548|issn=1600-6135}} 6. ^{{Cite journal|last=Muehlenbachs|first=Atis|last2=Bhatnagar|first2=Julu|last3=Agudelo|first3=Carlos A.|last4=Hidron|first4=Alicia|last5=Eberhard|first5=Mark L.|last6=Mathison|first6=Blaine A.|last7=Frace|first7=Michael A.|last8=Ito|first8=Akira|last9=Metcalfe|first9=Maureen G.|date=2015-11-05|title=Malignant Transformation of Hymenolepis nana in a Human Host|journal=The New England Journal of Medicine|volume=373|issue=19|pages=1845–1852|doi=10.1056/NEJMoa1505892|issn=1533-4406|pmid=26535513}} 7. ^{{cite journal| title = Genetic analysis of a sarcoma accidentally transplanted from a patient to a surgeon. | url = http://content.nejm.org/cgi/content/extract/335/20/1494 | year = 1996 | journal = New England Journal of Medicine | pages = 1494–1497 | volume = 335 | issue = 20 | last1 = Gärtner | first1 = Hermine-Valeria | last2 = Seidl | first2 = Christian | last3 = Luckenbach | first3 = Christine | last4 = Schumm | first4 = Georg | last5 = Seifried | first5 = Erhard | last6 = Ritter | first6 = Horst | last7 = Bültmann | first7 = Burkhard | accessdate = 2009-03-29 | pmid = 8890100 | doi=10.1056/NEJM199611143352004 }} 8. ^{{cite journal|last1=Rebbeck|first1=CA|last2=Thomas|first2=R|last3=Breen|first3=M|last4=Leroi|first4=AM|last5=Burt|first5=A|title=Origins and evolution of a transmissible cancer.|journal=Evolution|date=September 2009|volume=63|issue=9|pages=2340–9|doi=10.1111/j.1558-5646.2009.00724.x|pmid=19453727}} 9. ^{{cite journal|last1=Strakova|first1=A|last2=Murchison|first2=EP|title=The cancer which survived: insights from the genome of an 11000 year-old cancer.|journal=Current Opinion in Genetics & Development|date=February 2015|volume=30|pages=49–55|doi=10.1016/j.gde.2015.03.005|pmid=25867244|url=https://www.repository.cam.ac.uk/bitstream/1810/247911/1/Strakova_Murchison-2015-Current_Opinion_in_Genetics_%26_Development.pdf}} 10. ^{{cite journal | last = Belov | first = Katherine |title=The role of the Major Histocompatibility Complex in the spread of contagious cancers |journal=Mammalian Genome |volume=22 |issue=1–2 |pages=83–90 |date=February 2011 |pmid=20963591 |doi=10.1007/s00335-010-9294-2}} 11. ^{{cite journal | doi=10.1073/pnas.0704580104 | title=Transmission of a fatal clonal tumor by biting occurs due to depleted MHC diversity in a threatened carnivorous marsupial |year=2007 |last1=Siddle |first1=H. V. |last2=Kreiss |first2=A. |last3=Eldridge |first3=M. D. B. |last4=Noonan |first4=E. |last5=Clarke |first5=C. J. |last6=Pyecroft |first6=S. |last7=Woods |first7=G. M. |last8=Belov |first8=K. |journal=Proceedings of the National Academy of Sciences |volume=104 |issue=41 |pages=16221–6 |pmid=17911263 |pmc=1999395}} 12. ^{{cite journal |last1 = Murgia | first1 = Claudio | authorlink2 = Jonathan K. Pritchard | last2 = Pritchard | first2 = Jonathan K. | last3 = Kim | first3 = Su Yeon | last4 = Fassati | first4 = Ariberto | last5 = Weiss | first5 = Robin A. |title=Clonal origin and evolution of a transmissible cancer |journal=Cell |volume=126 |issue=3 |pages=477–487 |date=11 August 2006 |pmid=16901782 |doi=10.1016/j.cell.2006.05.051 | url = http://www.cell.com/cell/abstract/S0092-8674(06)00912-3 |pmc=2593932}} 13. ^{{cite journal| last=Cooper | first= Herbert L. | date = 1964-10-01| title=Chromosome Studies of a Contagious Reticulum Cell Sarcoma of the Syrian Hamster | journal=Journal of the National Cancer Institute| volume=33| issue = 4 | pages=691–706| pmid=14220251| last2=MacKay| first2=Carol M. | last3=Banfield| first3=William G. | doi = 10.1093/jnci/33.4.691 }} 14. ^{{cite journal |last=Banfield |first=William G. |date=1965-05-28 |title=Mosquito transmission of a reticulum cell sarcoma of hamsters |journal=Science |volume=148 |pages=1239–1240 |pmid=14280009 |doi=10.1126/science.148.3674.1239 |url=http://www.sciencemag.org/cgi/content/abstract/148/3674/1239 |last2=Woke |first2=PA |last3=MacKay |first3=CM |last4=Cooper |first4=HL |issue=3674}} 15. ^{{cite journal | last1 = Pearse | first1 = Anne-Maree | last2 = Swift | first2 = K. | title= Allograft theory: Transmission of devil facial-tumour disease | journal=Nature | date = 2 February 2006 | volume=439 | issue=7076| pages= 549 | pmid=16452970 | url=http://www.nature.com/nature/journal/v439/n7076/abs/439549a.html | doi= 10.1038/439549a }} 16. ^{{cite journal | url = http://phenomena.nationalgeographic.com/2015/04/09/selfish-shellfish-cells-cause-contagious-clam-cancer/ | title = Selfish shellfish cells cause contagious clam cancer | authorlink = Ed Yong | first = Ed | last = Yong | journal = National Geographic | date = April 9, 2015 | accessdate = April 10, 2015 }} 17. ^{{cite journal |authors= Michael J. Metzger, Carol Reinisch, James Sherry, Stephen P. Goff |title=Horizontal transmission of clonal cancer cells causes leukemia in soft-shell clams |journal=Cell |volume=161 |issue=2 |pages=255–63 |year=2015 |doi=10.1016/j.cell.2015.02.042 |pmid=25860608 |pmc=4393529}} 18. ^{{cite journal|authors= Michael J. Metzger, Antonio Villalba, María J. Carballal, David Iglesias, James Sherry, Carol Reinisch, Annette F. Muttray, Susan A. Baldwin, Stephen P. Goff |title=Widespread transmission of independent cancer lineages within multiple bivalve species |journal= Nature |volume=534 |issue=7609 |pages=705–9 |year=2016 |doi=10.1038/nature18599 |pmid=27338791 |pmc=4939143}} 19. ^{{cite journal|last1=Frierman|first1=EM|last2=Andrews|first2=JD|title=Occurrence of hematopoietic neoplasms in Virginia oysters (Crassostrea virginica).|journal=Journal of the National Cancer Institute|date=February 1976|volume=56|issue=2|pages=319–24|pmid=1255763}} External links
2 : Carcinogenesis|Clonally transmissible cancers |
随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。