| 词条 | Coronavirus 3' UTR pseudoknot |
| 释义 |
| Name = Coronavirus 3' UTR pseudoknot | image = RF00165.jpg | width = | caption = Predicted secondary structure and sequence conservation of Corona_pk3 | Symbol = Corona_pk3 | AltSymbols = | Rfam = RF00165 | miRBase = | miRBase_family = | RNA_type = Cis-reg | Tax_domain = Viruses | GO = | SO = {{SO|0000205}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }} The Coronavirus 3' UTR pseudoknot is an RNA structure found in the coronavirus genome. Coronaviruses contain 30 kb single-stranded positive-sense RNA genomes. The 3' UTR region of these coronavirus genomes contains a conserved ~55 nucleotide pseudoknot structure which is necessary for viral genome replication.[1] The mechanism of cis-regulation is unclear, but this element is postulated to function in the plus-strand. Other RNA families identified in the coronavirus include the coronavirus SL-III cis-acting replication element (CRE), the coronavirus frameshifting stimulation element, the coronavirus 3' stem-loop II-like motif (s2m) and the coronavirus packaging signal. References1. ^{{cite journal | last = Williams | first = GD |author2=Chang RY|author3=Brian DA | year = 1999 | title = A phylogenetically conserved hairpin-type 3' untranslated region pseudoknot functions in coronavirus RNA replication | journal = J Virol | volume = 73 | pages = 8349–8355 | pmid = 10482585 | issue = 10 | pmc = 112852}} External links
2 : Cis-regulatory RNA elements|Coronaviridae |
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