“Corticosteroid side-chain-isomerase”的意思、由来-开放百科全书

词条

Corticosteroid side-chain-isomerase

释义

References

{{enzyme
| Name = corticosteroid side-chain-isomerase
| EC_number = 5.3.1.21
| CAS_number = 75139-73-0
| IUBMB_EC_number = 5/3/1/21
| GO_code = 0004110
| image =
| width =
| caption =
}}

In enzymology, a corticosteroid side-chain-isomerase ({{EC number|5.3.1.21}}) is an enzyme that catalyzes the chemical reaction

11-deoxycorticosterone 20-hydroxy-3-oxopregn-4-en-21-al

Hence, this enzyme has one substrate, 11-deoxycorticosterone, and one product, 20-hydroxy-3-oxopregn-4-en-21-al.

This enzyme belongs to the family of isomerases, specifically those intramolecular oxidoreductases interconverting aldoses and ketoses. The systematic name of this enzyme class is 11-deoxycorticosterone aldose-ketose-isomerase.

References

{{cite journal | vauthors = Martin KO, Oh SW, Lee HJ, Monder C | date = 1977 | title = Studies on 21-3H-labeled corticosteroids: evidence for isomerization of the ketol side chain of 11-deoxycorticosterone by a hamster liver enzyme | journal = Biochemistry | volume = 16 | pages = 3803–9 | pmid = 901753 | doi = 10.1021/bi00636a013 | issue = 17 }}
{{cite journal | vauthors = Monder C, Martin KO, Bogumil J | date = 1980 | title = Presence of epimerase activity in hamster liver corticosteroid side chain isomerase | journal = J. Biol. Chem. | volume = 255 | pages = 7192–8 | pmid = 7391077 | issue = 15 }}

2 : EC 5.3.1|Enzymes of unknown structure

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。