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词条 Co-tenidone
释义

  1. Formulation

  2. References

  3. Footnotes

{{Drugbox
| verifiedrevid = 443540052
| type = combo
| component1 = Atenolol
| class1 = Beta blocker
| component2 = Chlortalidone
| class2 = Thiazide diuretic
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK = POM
| legal_US =
| legal_status =
| routes_of_administration = Oral
| CAS_number =
| ATC_prefix =
| ATC_suffix =
| PubChem =
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}}
| ChemSpiderID = 151231
}}Co-tenidone (BAN) is a non-proprietary name used to denote a combination of atenolol and chlortalidone. Co-tenidone is used in the treatment of hypertension. The use of β-blockers in hypertension was downgraded in June 2006 in the United Kingdom to fourth-line because they perform less well than other drugs, and because atenolol, the most frequently used β-blocker, at usual doses carries an unacceptable risk of provoking type 2 diabetes.[1]

Formulation

Two strengths of co-tenidone are currently available in the UK:

  • 50 mg atenolol and 12.5 mg chlortalidone, BAN of Co-tenidone 50/12.5
  • 100 mg atenolol and 25 mg chlortalidone, BAN of Co-tenidone 100/25

References

  • British National Formulary 54, September 2007

Footnotes

1. ^{{cite web | author= Sheetal Ladva | title=NICE and BHS launch updated hypertension guideline | url=https://www.nice.org.uk/guidance/cg34/resources/nice-and-the-british-hypertension-society-launch-updated-guideline-to-tackle-hypertension-in-england-and-wales- | date=2006-06-28 | publisher=National Institute for Health and Clinical Excellence | accessdate=}}
{{Antihypertensives and diuretics}}

3 : Beta blockers|Thiazides|Combination drugs

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