Crile may refer to:

• Crile (crater), a lunar crater
• Crile (tool), a type of hemostat
• George Washington Crile (1864–1943), American surgeon
• George Crile, Jr. (1907-1992), American surgeon
• George Crile III (1945–2006), American journalist
• Susan Crile (born 1942), American painter and printmaker

• South Charford
• South Charleston High School
• South Charleston Mound
• South Charnwood High School
• South Charter Street Historic District
• Southchase
• South Cheatham Advocate
• South Cheshire College
• South Cheshire (UK Parliament constituency)
• South Cheshire Way
• South Chicago (93rd Street) station
• South chicago and indiana harbor
• South Chicago and Indiana Harbor Railway
• South Chicago (Metra)
• South chilcotin
• South Chilcotin Provincial Park
• South China A.A.
• South China AA Sports Complex
• South China AA Stadium
• South China Agricultural University
• South China Athletic Club
• South China catshark
• South China Church
• South China (continent)
• South China cookiecutter shark