“Crotonoyl-(acyl-carrier-protein) hydratase”的意思、由来-开放百科全书

词条

Crotonoyl-(acyl-carrier-protein) hydratase

释义

References

{{enzyme
| Name = crotonoyl-[acyl-carrier-protein] hydratase
| EC_number = 4.2.1.58
| CAS_number = 9030-78-8
| IUBMB_EC_number = 4/2/1/58
| GO_code = 0047450
| image =
| width =
| caption =
}}

In enzymology, a crotonoyl-[acyl-carrier-protein] hydratase ({{EC number|4.2.1.58}}) is an enzyme that catalyzes the chemical reaction

(3R)-3-hydroxybutanoyl-[acyl-carrier-protein] but-2-enoyl-[acyl-carrier-protein] + H₂O

Hence, this enzyme has one substrate, (3R)-3-hydroxybutanoyl-[acyl-carrier-protein], and two products, but-2-enoyl-[acyl-carrier-protein] and H₂O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is (3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase (but-2-enoyl-[acyl-carrier protein]-forming). Other names in common use include (3R)-3-hydroxybutanoyl-[acyl-carrier-protein] hydro-lyase, beta-hydroxybutyryl acyl carrier protein dehydrase, beta-hydroxybutyryl acyl carrier protein (ACP) dehydrase, beta-hydroxybutyryl acyl carrier protein dehydrase, enoyl acyl carrier protein hydrase, crotonyl acyl carrier protein hydratase, 3-hydroxybutyryl acyl carrier protein dehydratase, beta-hydroxybutyryl acyl carrier, and protein dehydrase. This enzyme participates in fatty acid biosynthesis.

References

{{cite journal | vauthors = MAJERUS PW, ALBERTS AW, VAGELOS PR | date = 1965 | title = ACYL CARRIER PROTEIN. 3. AN ENOYL HYDRASE SPECIFIC FOR ACYL CARRIER PROTEIN THIOESTERS | journal = J. Biol. Chem. | volume = 240 | pages = 618–21 | pmid = 14275113 }}
{{cite journal | vauthors = Mizugaki M, Weeks G, Toomey RE, Wakil SJ | date = 1968 | title = Studies on the mechanism of fatty acid synthesis. XX. Preparation and general properties of beta-hydroxybutyryl acyl carrier protein dehydrase | journal = J. Biol. Chem. | volume = 243 | pages = 3661–70 | pmid = 5658542 | issue = 13 }}

2 : EC 4.2.1|Enzymes of unknown structure

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