| 词条 | Cytidine triphosphate |
| 释义 |
| verifiedrevid = 446646289 | ImageFile=CTP chemical structure.png | ImageSize=240px | ImageAlt = Skeletal formula of cytidine triphosphate as an anion (3- charge) | ImageFile1 = Cytidine triphosphate anion 3D spacefill.png | ImageSize1 = 220 | ImageAlt1 = Space-filling model of the cytidine triphosphate molecule as an anion (4- charge) | IUPACName=[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl(hydroxy-phosphonooxyphosphoryl)hydrogen phosphate | OtherNames=CTP; Cytidine-5'-triphosphate; Cytidine 5'-(tetrahydrogen triphosphate) |Section1={{Chembox Identifiers | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 19952488 | InChI = 1/C9H16N3O14P3/c10-5-1-2-12(9(15)11-5)8-7(14)6(13)4(24-8)3-23-28(19,20)26-29(21,22)25-27(16,17)18/h1-2,4,6-8,13-14H,3H2,(H,19,20)(H,21,22)(H2,10,11,15)(H2,16,17,18)/t4-,6-,7-,8-/m1/s1 | InChIKey = PCDQPRRSZKQHHS-XVFCMESIBL | InChI1 = 1/C9H13N3O5.3H3O4P/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;3*1-5(2,3)4/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);3*(H3,1,2,3,4)/t4-,6-,7-,8-;;;/m1.../s1 | InChIKey1 = NPIWPFUCEAMYFN-LLWADOMFBY | SMILES1 = OP(O)(=O)O.OP(O)(=O)O.OP(O)(=O)O.N/C1=N/C(=O)N(/C=C1)[C@@H]2O[C@H](CO)[C@@H](O)[C@H]2O | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C9H13N3O5.3H3O4P/c10-5-1-2-12(9(16)11-5)8-7(15)6(14)4(3-13)17-8;3*1-5(2,3)4/h1-2,4,6-8,13-15H,3H2,(H2,10,11,16);3*(H3,1,2,3,4)/t4-,6-,7-,8-;;;/m1.../s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = NPIWPFUCEAMYFN-LLWADOMFSA-N | CASNo=65-47-4 | CASNo_Ref = {{cascite|correct|CAS}} | PubChem=6176 | IUPHAR_ligand = 1741 | SMILES = c1cn(c(=O)nc1N)[C@H]2[C@@H]([C@@H]([C@H](O2)CO[P@](=O)(O)O[P@](=O)(O)OP(=O)(O)O)O)O | MeSHName = Cytidine+triphosphate |Section2={{Chembox Properties | Formula=C9H16N3O14P3 | MolarMass=483.156 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }} Cytidine triphosphate is a pyrimidine nucleoside triphosphate. CTP, much like ATP, consists of a ribose sugar, and three phosphate groups. The major difference between the two molecules is the base used, which in CTP is cytosine. CTP is a substrate in the synthesis of RNA. CTP is a high-energy molecule similar to ATP, but its role as an energy coupler is limited to a much smaller subset of metabolic reactions. CTP is a coenzyme in metabolic reactions like the synthesis of glycerophospholipids and glycosylation of proteins. CTP acts as an inhibitor of the enzyme aspartate carbamoyltransferase, which is used in pyrimidine biosynthesis.[1] See also
References1. ^Blackburn, G. Michael. Nucleic Acids in Chemistry and Biology. The Royal Society of Chemistry, 2006, p. 119-120. {{Nucleobases, nucleosides, and nucleotides}}{{Purinergics}}{{DEFAULTSORT:Cytidine Triphosphate}} 2 : Nucleotides|Pyrimidones |
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