词条 | Danielle Reed |
释义 |
|name = Danielle R. Reed |image = |image_size = 200 px |caption = |birth_date = |birth_place = |death_date = |death_place = |residence = Pennsylvania |citizenship = US |nationality = |ethnicity = |fields = Psychology, Genetics |workplaces = Monell Chemical Senses Center |alma_mater = Yale University |doctoral_advisor = Judith Rodin, Mark Friedman |academic_advisors = |doctoral_students = |notable_students = |known_for = Genetic variation in taste and obesity in mice and humans |author_abbrev_bot = |author_abbrev_zoo = |influences = |influenced = |awards = IFF Award, 2008 |religion = |signature = |footnotes = }} Danielle Renee Reed[1] is an American geneticist employed at the Monell Chemical Senses Center in Philadelphia, Pennsylvania. She is most notable for her papers regarding genetic variation in taste and obesity in mice and humans.{{Cn|date=January 2015}} Early life and educationReed has a Doctor of Philosophy in Psychology from Yale University, which she attended from 1984 to 1990.[2] Danielle Reed began her training as a scientist{{when?|date=January 2015}} in the laboratory of Stephen Woods at the University of Washington, studying the role of hormonal signals on food intake in rodents.{{Cn|date=January 2015}} She did her doctoral dissertation with Judith Rodin at Yale University and Mark Friedman (scientist)[https://www.monell.org/faculty/people/mark_friedman] at the Monell Chemical Senses Center, focusing on how rodent metabolism changes in response to short term exposure to high fat diets.{{Cn|date=January 2015}} As a postdoctoral fellow in the laboratory of Arlen Price at the University of Pennsylvania, she learned human genetics, focusing on mapping of genes for human obesity and taste using family-based linkage methods.{{Cn|date=January 2015}} CareerShe is most notable for her papers regarding genetic variation in taste and obesity in mice and humans.{{Cn|date=January 2015}} Reed's seminal studies on the genetics of bitter taste perception led to identification of a critical region of human Chromosome 5p15 whose variation correlated with a person's ability to taste the bitterness of PROP (propylthiouracil). This finding ultimately led to the discovery by Adler and co-workers (Charles Zuker) of a family of bitter taste receptors (taste receptor) located within this critical region of the chromosome.{{Cn|date=January 2015}} In 2008, Reed received the IFF Award For Outstanding Research On The Molecular Basis Of Taste in recognition of her contributions to the field, and delivered the IFF Lecture at the 2008 ACHemS meeting.{{Cn|date=January 2015}} She established her own laboratory in 2001 at the Monell Chemical Senses Center and her research is divided between genetic mapping of obesity loci in rodent models and human genetics of taste and smell.{{Cn|date=January 2015}} She teaches a summer class called "A Taste of Chemistry," which is sponsored in part by The Camille and Henry Dreyfus Foundation. She collaborates with Mee-Ra Rhyu from the Korean Food Research Institute on the biology of human salt perception.{{Cn|date=January 2015}} AwardsInternational Flavor and Fragrance Award for excellence in research, 2008{{Cn|date=January 2015}} Select publications
| last1 = Mennella | first1 = J. A. | last2 = Pepino | first2 = M. Y. | last3 = Duke | first3 = F. F. | last4 = Reed | first4 = D. R. | title = Psychophysical Dissection of Genotype Effects on Human Bitter Perception | doi = 10.1093/chemse/bjq106 | journal = Chemical Senses | volume = 36 | issue = 2 | pages = 161–167 | year = 2010 | pmid = 20980355 | pmc =3020389 }}
| last1 = Pelchat | first1 = M. L. | last2 = Bykowski | first2 = C. | last3 = Duke | first3 = F. F. | last4 = Reed | first4 = D. R. | title = Excretion and Perception of a Characteristic Odor in Urine after Asparagus Ingestion: A Psychophysical and Genetic Study | doi = 10.1093/chemse/bjq081 | journal = Chemical Senses | volume = 36 | issue = 1 | pages = 9–17 | year = 2010 | pmid = 20876394 | pmc =3002398 }}
| last1 = Reed | first1 = D. R. | last2 = Zhu | first2 = G. | last3 = Breslin | first3 = P. A. S. | last4 = Duke | first4 = F. F. | last5 = Henders | first5 = A. K. | last6 = Campbell | first6 = M. J. | last7 = Montgomery | first7 = G. W. | last8 = Medland | first8 = S. E. | last9 = Martin | first9 = N. G. | doi = 10.1093/hmg/ddq324 | last10 = Wright | first10 = M. J. | title = The perception of quinine taste intensity is associated with common genetic variants in a bitter receptor cluster on chromosome 12 | journal = Human Molecular Genetics | volume = 19 | issue = 21 | pages = 4278–4285 | year = 2010 | pmid = 20675712 | pmc =2951861 }}
| last1 = Reed | first1 = D. R. | last2 = Duke | first2 = F. F. | last3 = Ellis | first3 = H. K. | last4 = Rosazza | first4 = M. R. | last5 = Lawler | first5 = M. P. | last6 = Alarcon | first6 = L. K. | last7 = Tordoff | first7 = M. G. | doi = 10.1016/j.physbeh.2011.04.006 | title = Body fat distribution and organ weights of 14 common strains and a 22-strain consomic panel of rats | journal = Physiology & Behavior | volume = 103 | issue = 5 | pages = 523–529 | year = 2011 | pmid = 21504752 | pmc =3107863 }} References1. ^{{cite news |title=Picky Eaters: Expert Q&A|url=https://www.pbs.org/wgbh/nova/body/reed-taste.html |newspaper=Nova ScienceNow|location=United States |date=July 28, 2009|accessdate=January 12, 2015}} 2. ^http://www.monell.org/faculty/people/danielle_reed External links
4 : Year of birth missing (living people)|Living people|Yale University alumni|American geneticists |
随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识,基本涵盖了大多数领域的百科知识,是一部内容自由、开放的电子版国际百科全书。