| 词条 | David Eisenberg |
| 释义 |
| name = | native_name = | native_name_lang = | image = David Eisenberg - journal.pcbi.1003116.g001.png | image_size = | alt = | caption = David Eisenberg | birth_date = {{Birth date and age|1939|03|15}} | birth_place = Chicago, United States | death_date = | death_place = | resting_place = | resting_place_coordinates = | other_names = | residence = | citizenship = | nationality = | fields = Proteins[1] Amyloid[2] Structural biology[3][4][5] | workplaces = Howard Hughes Medical Institute University of Oxford University of California, Los Angeles Harvard University California Institute of Technology Princeton University | alma_mater = Harvard University (undergraduate) The Queen's College, Oxford (postgraduate) | thesis_title = Some problems in the electronic structure of molecules | thesis_url = http://solo.bodleian.ox.ac.uk/primo_library/libweb/action/dlDisplay.do?docId=oxfaleph019444285 | thesis_year =1965 | doctoral_advisor =Charles Coulson{{citation needed|date=June 2013}} | academic_advisors = | doctoral_students = Michael Gribskov{{citation needed|date=June 2013}} | notable_students = Charlotte Deane[6] | known_for = | awards = Harvey Prize (2008) ISCB Senior Scientist Award (2013)[7] | signature = | signature_alt = | website = {{Plainlist|
}} | spouse = | children = }}David S. Eisenberg (born 15 March 1939{{citation needed|date=June 2013}}) is an American biochemist and biophysicist best known for his contributions to structural biology and computational molecular biology. A professor at the University of California, Los Angeles since the early 1970s and director of the UCLA-DOE Institute for Genomics & Proteomics since the early 1990s, as well as a member of the California NanoSystems Institute (CNSI) at UCLA.[8][9][10][11][12][13][14] EducationEisenberg attended Harvard University and graduated in 1961 with an A.B. in Biochemical Sciences. He went on to the University of Oxford, where he was awarded a D.Phil in 1965[15] for research supervised by Charles Coulson. ResearchEisenberg's current research focuses on the structural biology of amyloidogenic proteins, while his computational efforts largely center on the development of bioinformatic/proteomic methodologies for elucidation and analysis of protein interaction networks. His research group hosts the Database of Interacting Proteins.[16] Career
AwardsHe was the recipient of Harvey Prize (Human Health) 2008 in recognition of his contributions in unfolding the structure of amyloid fibrils. The award was presented to him at a ceremony that took place on March 23, 2009 at the Technion. This recently recognized protein state provides opportunities to understand cells in health and disease.[17]
References1. ^{{Cite journal | last1 = Eisenberg | first1 = D. | authorlink1= David Eisenberg| last2 = McLachlan | first2 = A. D. | doi = 10.1038/319199a0 | title = Solvation energy in protein folding and binding | journal = Nature | volume = 319 | issue = 6050 | pages = 199–203 | year = 1986 | pmid = 3945310| pmc = }} {{Repligen Corporation Award in Chemistry of Biological Processes}}{{ISCB Fellows}}{{Authority control}}{{DEFAULTSORT:Eisenberg, David}}2. ^{{Cite journal | last1 = Balbirnie | first1 = M. | last2 = Grothe | first2 = R. | last3 = Eisenberg | first3 = D. S. | doi = 10.1073/pnas.041617698 | title = An amyloid-forming peptide from the yeast prion Sup35 reveals a dehydrated beta -sheet structure for amyloid | journal = Proceedings of the National Academy of Sciences | volume = 98 | issue = 5 | pages = 2375–2380 | year = 2001 | pmid = 11226247 | pmc =30146 }} 3. ^{{Cite journal | last1 = Lüthy | first1 = R. | last2 = Bowie | first2 = J. U. | last3 = Eisenberg | first3 = D. | doi = 10.1038/356083a0 | title = Assessment of protein models with three-dimensional profiles | journal = Nature | volume = 356 | issue = 6364 | pages = 83–85 | year = 1992 | pmid = 1538787 | pmc = }} 4. ^{{Cite journal | doi = 10.1126/science.3133767 | last1 = Chapman | first1 = M. S. | last2 = Suh | first2 = S. W. | last3 = Curmi | first3 = P. M. | last4 = Cascio | first4 = D. | last5 = Smith | first5 = W. W. | last6 = Eisenberg | first6 = D. S. | title = Tertiary structure of plant RuBisCO: Domains and their contacts | journal = Science | volume = 241 | issue = 4861 | pages = 71–74 | year = 1988 | pmid = 3133767}} 5. ^{{GoogleScholar|DLXzRi8AAAAJ}} 6. ^http://eisenberglab.mbi.ucla.edu/?page_id=87 7. ^{{Cite journal | last1 = Fogg | first1 = C. N. | last2 = Kovats | first2 = D. E. | doi = 10.1371/journal.pcbi.1003116 | title = International Society for Computational Biology Honors David Eisenberg with 2013 Accomplishment by a Senior Scientist Award | journal = PLoS Computational Biology | volume = 9 | issue = 6 | pages = e1003116 | year = 2013 | pmc =3681620 }} 8. ^HHMI profile of David Eisenberg 9. ^The Eisenberg research lab at UCLA 10. ^UCLA-DOE Institute for Genomics & Proteomics 11. ^{{YouTube|S7U-nXAWtvs|David Eisenberg’s speech during the Harvey Prize ceremony}} 12. ^{{cite book |author1=Eisenberg, David |author2=Kauzmann, Walter |title=The structure and properties of water |publisher=Clarendon Press |location=Oxford |year=2005 |pages= |isbn=0-19-857026-0 |oclc= |doi= |accessdate=}} 13. ^{{AcademicSearch|926759}} 14. ^{{Scopus|id=19434183500}} 15. ^{{cite thesis |degree=PhD |first=David J.|last=Eisenberg |title=Some problems in the electronic structure of molecules |publisher=University of Oxford |date=1965 |url=http://solo.bodleian.ox.ac.uk/primo_library/libweb/action/dlDisplay.do?docId=oxfaleph019444285|authorlink=David Eisenberg}} 16. ^{{Cite journal | last1 = Salwinski | first1 = L. | last2 = Miller | first2 = C. S. | last3 = Smith | first3 = A. J. | last4 = Pettit | first4 = F. K. | last5 = Bowie | first5 = J. U. | last6 = Eisenberg | first6 = D. | authorlink6 = David Eisenberg| title = The Database of Interacting Proteins: 2004 update | doi = 10.1093/nar/gkh086 | journal = Nucleic Acids Research | volume = 32 | issue = 90001 | pages = D449–D451 | year = 2004 | pmid = 14681454 | pmc =308820 }} 17. ^Harvey Prize Award 10 : 1939 births|Living people|Harvard University alumni|Howard Hughes Medical Investigators|American biophysicists|Jewish American scientists|University of California, Los Angeles faculty|Members of the United States National Academy of Sciences|Guggenheim Fellows|Fellows of the International Society for Computational Biology |
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