| 词条 | Deoxycytidine triphosphate |
| 释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 447271417 | ImageFile=Desoxycytidintriphosphat protoniert.svg | ImageSize=240 | ImageAlt = Skeletal formula of deoxycytidine triphosphate | ImageFile1 = Deoxycytidine triphosphate anion 3D spacefill.png | ImageSize1 = 220 | ImageAlt1 = Space-filling model of the deoxycytidine triphosphate molecule as an anion (4- charge) | IUPACName= | OtherNames= |Section1={{Chembox Identifiers | CASNo_Ref = {{cascite|correct|CAS}} | CASNo=2056-98-6 | PubChem=65091 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 58601 | SMILES = C1[C@@H]([C@H](O[C@H]1N2C=CC(=NC2=O)N)CO[P@@](=O)(O)O[P@@](=O)(O)OP(=O)(O)O)O | InChI = 1/C9H16N3O13P3/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1 | InChIKey = RGWHQCVHVJXOKC-SHYZEUOFBW | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C9H16N3O13P3/c10-7-1-2-12(9(14)11-7)8-3-5(13)6(23-8)4-22-27(18,19)25-28(20,21)24-26(15,16)17/h1-2,5-6,8,13H,3-4H2,(H,18,19)(H,20,21)(H2,10,11,14)(H2,15,16,17)/t5-,6+,8+/m0/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = RGWHQCVHVJXOKC-SHYZEUOFSA-N |Section2={{Chembox Properties | C=9 | H=16 | N=3 | O=13 | P=3 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }} Deoxycytidine triphosphate (dCTP) is a nucleoside triphosphate that contains the pyrimidine base cytosine. The triphosphate group contains high-energy phosphoanhydride bonds, which liberate energy when hydrolized. DNA polymerase enzymes use this energy to incorporate deoxycytidine into a newly synthesized strand of DNA. A chemical equation can be written that represents the process: (DNA)n + dCTP ↔ (DNA)n-C + PPi That is, dCTP has the PPi (pyrophosphate) cleaved off and the dCMP is incorporated into the DNA strand at the 3' end. Subsequent hydrolysis of the PPi drives the equilibrium of the reaction toward the right side, i.e. incorporation of the nucleotide in the growing DNA chain. Like other nucleoside triphosphates, manufacturers recommend that dCTP be stored in aqueous solution at −20 °C.[1] See also
References1. ^{{cite web | url=http://www.bioline.com/media/pdf/dNTP_GBLV2.pdf | title=Definitive Guide to dNTPs | accessdate=July 29, 2017}} External links
3 : Molecular biology|Nucleotides|Pyrimidones |
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