| 词条 | Diampromide |
| 释义 |
| verifiedrevid = 447990682 | IUPAC_name = N-[2-(methyl-(2-phenylethyl)amino)propyl]-N-phenylpropanamide | image = Diampromide.svg | width = 180 | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = S9 | legal_DE = Anlage I | legal_CA = Schedule I | legal_UK = | legal_US = Schedule I | legal_UN = P I | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | elimination_half-life = | excretion = | CAS_number = 552-25-0 | ATC_prefix = none | ATC_suffix = | PubChem = 62370 | ChEMBL = 2106220 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = DB01502 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 56158 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = 26G7YC77BU | C=21 | H=28 | N=2 | O=1 | molecular_weight = 324.46 g/mol | smiles = CCC(=O)N(CC(C)N(C)CCc1ccccc1)c1ccccc1 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C21H28N2O/c1-4-21(24)23(20-13-9-6-10-14-20)17-18(2)22(3)16-15-19-11-7-5-8-12-19/h5-14,18H,4,15-17H2,1-3H3 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = RXTHKWVSXOIHJS-UHFFFAOYSA-N | synonyms = Diampromide }}Diampromide[1] is an opioid analgesic from the ampromide family of drugs, related to other drugs such as propiram and phenampromide. It was invented in the 1960s by American Cyanamid,[2] and can be described as a ring-opened analogue of fentanyl. Diampromide produces similar effects to other opioids, including analgesia, sedation, dizziness and nausea, and is around the same potency as morphine.[3] Diampromide is in Schedule I of the Controlled Substances Act 1970 of the United States as a Narcotic with ACSCN 9615 with a zero aggregate manufacturing quota as of 2014. [4] It is listed under the Single Convention for the Control of Narcotic Substances 1961 and is controlled in most countries in the same fashion as is morphine. It is highly poisonous. References1. ^US 2944081 {{Opioidergics}}{{analgesic-stub}}2. ^US Patent 2944081 3. ^Ivanovic MD, Micovic IV, Vuckovic S, Prostran M, Todorovic Z, Ivanovic ER, Kiricojevic VD, Djordjevic JB, Dosen-Micovic LJ. The synthesis and pharmacological evaluation of 2,3-seco-fentanyl analogues. Journal of the Serbian Chemical Society. 2004; 69(11): 955-968. 4. ^http://www.deadiversion.usdoj.gov/fed_regs/quotas/2014/fr0825.htm 4 : Synthetic opioids|Propionamides|Anilines|Mu-opioid agonists |
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