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词条 Dibromotyrosine
释义

  1. References

{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 443636030
| IUPAC_name = (2S)-2-Amino-3-(3,5-dibromo-4-hydroxyphenyl)propanoic acid
| image = 3,5-Dibromo-L-tyrosine.svg
| tradename =
| pregnancy_AU =
| pregnancy_US =
| pregnancy_category =
| legal_AU =
| legal_CA =
| legal_UK =
| legal_US =
| legal_status =
| routes_of_administration =
| bioavailability =
| protein_bound =
| metabolism =
| elimination_half-life =
| excretion =
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 300-38-9
| ATC_prefix = H03
| ATC_suffix = BX02
| PubChem = 67532
| DrugBank_Ref = {{drugbankcite|correct|drugbank}}
| DrugBank =
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 28335
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = QD49LEP46E
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 60854
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 1232132
| smiles = Brc1cc(cc(Br)c1O)C[C@@H](C(=O)O)N
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C9H9Br2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = COESHZUDRKCEPA-ZETCQYMHSA-N
| C=9 | H=9 | Br=2 | N=1 | O=3
| molecular_weight = 338.981 g/mol
}}

Dibromotyrosine is an antithyroid preparation and a derivative of the natural amino acid tyrosine.

It is formed by eosinophil peroxidase.[1]

References

1. ^{{cite journal |vauthors=Kambayashi Y, Ogino K, Takemoto K |title=Preparation and Characterization of a Polyclonal Antibody against Brominated Protein |journal=J Clin Biochem Nutr |volume=44 |issue=1 |pages=95–103 |date=January 2009 |pmid=19177194 |pmc=2613505 |doi=10.3164/jcbn.08-196 |url=|display-authors=etal}}
{{Thyroid therapy}}{{systemic-hormonal-drug-stub}}

2 : Amino acid derivatives|Organobromides

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