词条 | Dibromotyrosine |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 443636030 | IUPAC_name = (2S)-2-Amino-3-(3,5-dibromo-4-hydroxyphenyl)propanoic acid | image = 3,5-Dibromo-L-tyrosine.svg | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = {{cascite|correct|??}} | CAS_number = 300-38-9 | ATC_prefix = H03 | ATC_suffix = BX02 | PubChem = 67532 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChEBI_Ref = {{ebicite|changed|EBI}} | ChEBI = 28335 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = QD49LEP46E | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 60854 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1232132 | smiles = Brc1cc(cc(Br)c1O)C[C@@H](C(=O)O)N | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C9H9Br2NO3/c10-5-1-4(2-6(11)8(5)13)3-7(12)9(14)15/h1-2,7,13H,3,12H2,(H,14,15)/t7-/m0/s1 | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = COESHZUDRKCEPA-ZETCQYMHSA-N | C=9 | H=9 | Br=2 | N=1 | O=3 | molecular_weight = 338.981 g/mol }} Dibromotyrosine is an antithyroid preparation and a derivative of the natural amino acid tyrosine. It is formed by eosinophil peroxidase.[1] References1. ^{{cite journal |vauthors=Kambayashi Y, Ogino K, Takemoto K |title=Preparation and Characterization of a Polyclonal Antibody against Brominated Protein |journal=J Clin Biochem Nutr |volume=44 |issue=1 |pages=95–103 |date=January 2009 |pmid=19177194 |pmc=2613505 |doi=10.3164/jcbn.08-196 |url=|display-authors=etal}} {{Thyroid therapy}}{{systemic-hormonal-drug-stub}} 2 : Amino acid derivatives|Organobromides |
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