| 词条 | DicF RNA |
| 释义 |
| Name = DicF RNA | image = RF00039.jpg | width = | caption = Predicted secondary structure and sequence conservation of DicF | Symbol = DicF | AltSymbols = | Rfam = RF00039 | miRBase = | miRBase_family = | RNA_type = Gene; antisense | Tax_domain = Bacteria | GO = {{GO|0003729}} | SO = {{SO|0000644}} | CAS_number = | EntrezGene = | HGNCid = | OMIM = | PDB = | RefSeq = | Chromosome = | Arm = | Band = | LocusSupplementaryData = }}DicF RNA is a non-coding RNA that is an antisense inhibitor of cell division gene ftsZ.[1] DicF is bound by the Hfq protein which enhances its interaction with its targets. Pathogenic E. coli strains possess multiple copies of sRNA DicF in their genomes, while no-pathogenic strains do not.DicF and Hfq are both necessary to reduce FtsZ protein levels, leading to cell filamentation under anaerobic conditions.[2] References1. ^{{cite journal | last = Faubladier | first = M |author2=Bouche JP | year = 1994 | title = Division inhibition gene dicF of Escherichia coli reveals a widespread group of prophage sequences in bacterial genomes | journal = J Bacteriol | volume = 176 | pages = 1150–1156 | pmid = 7508908 | issue = 4 | pmc = 205167}} 2. ^{{Cite journal|last=Murashko|first=Oleg N.|last2=Lin-Chao|first2=Sue|date=2017-09-19|title=Escherichia coli responds to environmental changes using enolasic degradosomes and stabilized DicF sRNA to alter cellular morphology|journal=Proceedings of the National Academy of Sciences of the United States of America|volume=114|issue=38|pages=E8025–E8034|doi=10.1073/pnas.1703731114|issn=1091-6490|pmid=28874523|pmc=5617263}} Further reading
| doi = 10.1007/BF02190800 | pmid = 7651342 | year = 1995 | last1 = Cam | first1 = K. | last2 = Cuzange | first2 = A. | last3 = Bouché | first3 = J. P. | title = Sigma S-dependent overexpression of ftsZ in an Escherichia coli K-12 rpoB mutant that is resistant to the division inhibitors DicB and DicF RNA | volume = 248 | issue = 2 | pages = 190–194 | journal = Molecular & general genetics : MGG }}
| doi = 10.1016/0022-2836(90)90325-G | pmid = 1691299 | year = 1990 | last1 = Faubladier | first1 = M. | last2 = Cam | first2 = K. | last3 = Bouché | first3 = J. P. | title = Escherichia coli cell division inhibitor DicF-RNA of the dicB operon. Evidence for its generation in vivo by transcription termination and by RNase III and RNase E-dependent processing | volume = 212 | issue = 3 | pages = 461–471 | journal = Journal of Molecular Biology }} External links
1 : Non-coding RNA |
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