| 词条 | Diflorasone diacetate |
| 释义 |
| Verifiedfields = changed | verifiedrevid = 460785642 | IUPAC_name = [17-(2-Acetyloxyacetyl)- 6,9-difluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,11,12,14,15,16- octahydrocyclopenta[a]phenanthren-17-yl] acetate | image = Diflorasone diacetate.png | tradename = Psorcon | Drugs.com = {{drugs.com|monograph|psorcon}} | MedlinePlus = a602019 | pregnancy_AU = | pregnancy_US = C | legal_AU = | legal_UK = | legal_US = Rx-only | routes_of_administration = Topical | IUPHAR_ligand = 7068 | CAS_number_Ref = {{cascite|changed|??}} | CAS_number = 2557-49-5 | ATC_prefix = D07 | ATC_suffix = AC10 | ChEBI_Ref = {{ebicite|correct|EBI}} | ChEBI = 31483 | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C26H32F2O7/c1-13-8-17-18-10-20(27)19-9-16(31)6-7-23(19,4)25(18,28)21(32)11-24(17,5)26(13,35-15(3)30)22(33)12-34-14(2)29/h6-7,9,13,17-18,20-21,32H,8,10-12H2,1-5H3/t13-,17-,18-,20-,21-,23-,24-,25-,26-/m0/s1 | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = BOBLHFUVNSFZPJ-JOYXJVLSSA-N | PubChem = 71414 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = DB00223 | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 64504 | UNII_Ref = {{fdacite|correct|FDA}} | UNII = T2DHJ9645W | KEGG_Ref = {{keggcite|correct|kegg}} | KEGG = D01327 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 1201380 | C=26 | H=32 | F=2 | O=7 | molecular_weight = 494.525 g/mol }}Diflorasone diacetate is a topical steroid that comes in the form of a cream. It is manufactured by E. Fougera & Co. and is used as an anti-inflammatory and anti-itching agent, like other topical corticosteroids. It is prescribed for psoriasis[1] and atopic dermatitis, among other conditions. With respect to potency, it is regarded as a Class I steroid (of classes I–IV).[2] No long-term animal studies have been done to determine whether diflorasone diacetate could have carcinogenic properties.{{citation needed|date=April 2015}} Little data is available regarding whether diflorasone diacetate would be present in great enough quantities to cause harm to an infant.[3] References1. ^{{Cite journal | last1 = Shupack | first1 = J. L. | last2 = Jondreau | first2 = L. | last3 = Kenny | first3 = C. | last4 = Stiller | first4 = M. J. | title = Diflorasone diacetate ointment 0.05% versus betamethasone dipropionate ointment 0.05% in moderate-severe plaque-type psoriasis | journal = Dermatology | volume = 186 | issue = 2 | pages = 129–132 | year = 1993 | pmid = 8428041 | doi=10.1159/000247323}} {{Glucocorticoids}}{{Glucocorticoidics}}{{dermatologic-drug-stub}}2. ^psoriasis.org: [www.psoriasis.org/sublearn03_mild_potency] 3. ^Drugs.com: [https://www.drugs.com/mtm/diflorasone-topical.html Diflorasone topical] 4 : Corticosteroid esters|Corticosteroids|Organofluorides|Acetate esters |
| 随便看 |
|
开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。