| 词条 | Discovering Dengue Drugs – Together |
| 释义 |
Discovering Dengue Drugs – Together is divided into two phases.[2] Phase 1, launched August 21, 2007,[3] used AutoDock 2007 (the same software used for FightAIDS@Home) to test how well antiviral drug candidates are predicted to bind to the target virus's proteases. Compounds predicted to bind strongly (protease inhibitors) are potential antiviral drug candidates.[1] This phase ended in August 2009.[4] Phase 2 "will use a more computationally intensive program to screen the candidates that make it through Phase 1."[5] The drug candidates that make it through Phase 2 will then be lab-tested.[5] Like all World Community Grid projects, Discovering Dengue Drugs – Together uses a computational grid made up of thousands of client (computing) computers belonging to independent volunteers, in conjunction with servers that distribute portions of the work to the clients.[6][7] In 2008, the project was temporarily suspended because of Hurricane Ike.[8] Processing resumed in January 2009,[9] with the server function transferred from the University of Texas Medical Branch in Galveston to the Texas Advanced Computing Center in Austin.[10] References1. ^1 {{cite web|url=http://www.worldcommunitygrid.org/projects_showcase/dddt/viewDddtAbout.do|title=Discovering Dengue Drugs – Together: About the Project|publisher=World Community Grid|accessdate=2007-08-24}} 2. ^{{cite web|url=http://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=14561#109721|title=Re: Project about dengue ever|author=Didactylos|publisher=World Community Grid|date=2007-06-21|accessdate=2007-08-07}} 3. ^{{cite web|url=http://www.worldcommunitygrid.org/projects_showcase/viewResearch.do|title=Active Research|work=Research|publisher=World Community Grid|accessdate=2007-07-28}} 4. ^{{cite web|url=http://www.worldcommunitygrid.org/projects_showcase/dddt/viewDddtMain.do|publisher=World Community Grid|title=World Community Grid - Research - Discovering Dengue Drugs – Together}} 5. ^1 {{cite web|url=http://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=15192#114871|title=Re: Results...|author=lawrencehardin|publisher=World Community Grid|date=2007-07-10|accessdate=2007-08-07}} 6. ^See {{cite web|url=http://www.worldcommunitygrid.org/about_us/viewAboutUs.do|title=World Community Grid - About Us|accessdate=2009-01-27}} 7. ^See also {{cite web|url=http://www.worldcommunitygrid.org/about_us/viewGridComputingBasics.do|title=How Grid Computing Works|publisher=World Community Grid|accessdate=2009-01-27}} 8. ^{{cite web|url=http://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=21894|title=Discovering Dengue Drugs Together project slowed down because of hurricane|publisher=World Community Grid ("Known Issues" forum posting)}} 9. ^{{cite web|publisher=World Community Grid ("Member News" forum posting)|url=http://www.worldcommunitygrid.org/forums/wcg/viewthread?thread=24133|title=Work is being distributed for Discovering Dengue Drugs - Together}} 10. ^{{cite web|url=http://www.worldcommunitygrid.org/forums/wcg/printpost?post=211771|title=Update on Re-start|author=Stan Watowich|publisher=World Community Grid|date=forum posting, 01-19-2009}} External links
1 : Dengue fever |
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