词条 | DNQX |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 460112258 | Name = | ImageFile = DNQX.png | ImageSize = 180 | ImageAlt = Skeletal formula | ImageFile1 = DNQX molecule spacefill.png | ImageSize1 = 180 | ImageAlt1 = Space-filling model of DNQX | IUPACName = 6,7-Dinitroquinoxaline-2,3(1H,4H)-dione | OtherNames = | SystematicName = | Section1 = {{Chembox Identifiers | ChemSpiderID_Ref = {{chemspidercite|correct|chemspider}} | ChemSpiderID = 3123097 | PubChem = 3899541 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = | InChI = 1S/C8H4N4O6/c13-7-8(14)10-4-2-6(12(17)18)5(11(15)16)1-3(4)9-7/h1-2H,(H,9,13)(H,10,14) | InChIKey = RWVIMCIPOAXUDG-UHFFFAOYSA-N | StdInChI_Ref = {{stdinchicite|correct|chemspider}} | StdInChI = 1S/C8H4N4O6/c13-7-8(14)10-4-2-6(12(17)18)5(11(15)16)1-3(4)9-7/h1-2H,(H,9,13)(H,10,14) | StdInChIKey_Ref = {{stdinchicite|correct|chemspider}} | StdInChIKey = RWVIMCIPOAXUDG-UHFFFAOYSA-N | CASNo_Ref = {{cascite|changed|??}} | CASNo=2379-57-9 | UNII = 62T278S1MX | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = DB03759 | SMILES = O=c2[nH]c1cc(N(=O)=O)c(N(=O)=O)cc1[nH]c2=O }} | Section2 = {{Chembox Properties | C=8 | H=4 | N=4 | O=6 | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= | Section3 = {{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = | Section4 = | Section5 = | Section6 = }} DNQX (6,7-dinitroquinoxaline-2,3-dione) is a competitive antagonist at AMPA and kainate receptors, two ionotropic glutamate receptor (iGluR) subfamilies.[1] It is used in a variety of molecular biology subfields, notably neurophysiology, to assist researchers in determining the properties of various types of ion channels and their potential applications in medicine. See also
References1. ^{{cite journal | vauthors = Traynelis SF, Wollmuth LP, McBain CJ, Menniti FS, Vance KM, Ogden KK, Hansen KB, Yuan H, Myers SJ, Dingledine R | title = Glutamate receptor ion channels: structure, regulation, and function | journal = Pharmacological Reviews | volume = 62 | issue = 3 | pages = 405–96 | date = September 2010 | pmid = 20716669 | pmc = 2964903 | doi = 10.1124/pr.109.002451 }} External links
7 : AMPA receptor antagonists|Kainate receptor antagonists|NMDA receptor antagonists|Nitro compounds|Quinoxalines|Quinones|Lactams |
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