Casimir II may refer to:

• Casimir II the Just (1138–1194), Duke of Cracow and senior prince of Poland
• Casimir II, Duke of Pomerania (after 1130 – 1180), duke of Pomerania-Demmin
• Casimir II, Duke of Cieszyn (ca. 1449 – 1528)
• Casimir II of Zator (ca. 1450 – 1490)

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