“DTDP-6-deoxy-L-talose 4-dehydrogenase”的意思、由来-开放百科全书

词条

DTDP-6-deoxy-L-talose 4-dehydrogenase

释义

References

{{DISPLAYTITLE:dTDP-6-deoxy-L-talose 4-dehydrogenase}}{{enzyme
| Name = dTDP-6-deoxy-L-talose 4-dehydrogenase
| EC_number = 1.1.1.134
| CAS_number = 37250-65-0
| IUBMB_EC_number = 1/1/1/134
| GO_code = 0047003
| image =
| width =
| caption =
}}

In enzymology, a dTDP-6-deoxy-L-talose 4-dehydrogenase ({{EC number|1.1.1.134}}) is an enzyme that catalyzes the chemical reaction

dTDP-6-deoxy-L-talose + NADP⁺ dTDP-4-dehydro-6-deoxy-L-mannose + NADPH + H⁺

Thus, the two substrates of this enzyme are dTDP-6-deoxy-L-talose and NADP⁺, whereas its 3 products are dTDP-4-dehydro-6-deoxy-L-mannose, NADPH, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD⁺ or NADP⁺ as acceptor. The systematic name of this enzyme class is dTDP-6-deoxy-L-talose:NADP⁺ 4-oxidoreductase. Other names in common use include thymidine diphospho-6-deoxy-L-talose dehydrogenase, TDP-6-deoxy-L-talose dehydrogenase, thymidine diphospho-6-deoxy-L-talose dehydrogenase, and dTDP-6-deoxy-L-talose dehydrogenase (4-reductase). This enzyme participates in nucleotide sugars metabolism.

References

{{cite journal |vauthors=Gaugler RW, Gabriel O | date = 1973 | title = Biological mechanisms involved in the formation of deoxy sugars VII. Biosynthesis of 6-deoxy-L-talose | journal = J. Biol. Chem. | volume = 248 | pages = 6041–9 | pmid = 4199258 | issue = 17 }}

3 : EC 1.1.1|NADPH-dependent enzymes|Enzymes of unknown structure

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