“Dynorphin B”的意思、由来-开放百科全书

词条

Dynorphin B

释义

See also
References

{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 428952076
| ImageFile=Dynorphin B.svg
| ImageSize=300px
| IUPACName=
| OtherNames= Dynorphin B-13; Rimorphin
| Reference=^[1]
|Section1={{Chembox Identifiers
| CASNo_Ref = {{cascite|correct|??}}
| CASNo=85006-82-2
| PubChem=16133806
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 17299995
| SMILES = [H]/N=C(\)/NCCC[C@@H](C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)O)NC(=O)[C@H](CCCN/C(=N/[H])/N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](Cc2ccccc2)NC(=O)CNC(=O)CNC(=O)[C@H](Cc3ccc(cc3)O)N
| InChI = 1/C74H115N21O17/c1-40(2)34-53(91-68(107)54(36-44-18-10-8-11-19-44)86-58(100)39-84-57(99)38-85-62(101)48(76)35-46-25-27-47(97)28-26-46)67(106)89-51(24-17-33-83-74(80)81)63(102)87-50(23-16-32-82-73(78)79)64(103)90-52(29-30-56(77)98)65(104)92-55(37-45-20-12-9-13-21-45)69(108)88-49(22-14-15-31-75)66(105)93-59(41(3)4)70(109)94-60(42(5)6)71(110)95-61(43(7)96)72(111)112/h8-13,18-21,25-28,40-43,48-55,59-61,96-97H,14-17,22-24,29-39,75-76H2,1-7H3,(H2,77,98)(H,84,99)(H,85,101)(H,86,100)(H,87,102)(H,88,108)(H,89,106)(H,90,103)(H,91,107)(H,92,104)(H,93,105)(H,94,109)(H,95,110)(H,111,112)(H4,78,79,82)(H4,80,81,83)/t43-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60+,61+/m1/s1
| InChIKey = AGTSSZRZBSNTGQ-ITZCFHCWBN
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C74H115N21O17/c1-40(2)34-53(91-68(107)54(36-44-18-10-8-11-19-44)86-58(100)39-84-57(99)38-85-62(101)48(76)35-46-25-27-47(97)28-26-46)67(106)89-51(24-17-33-83-74(80)81)63(102)87-50(23-16-32-82-73(78)79)64(103)90-52(29-30-56(77)98)65(104)92-55(37-45-20-12-9-13-21-45)69(108)88-49(22-14-15-31-75)66(105)93-59(41(3)4)70(109)94-60(42(5)6)71(110)95-61(43(7)96)72(111)112/h8-13,18-21,25-28,40-43,48-55,59-61,96-97H,14-17,22-24,29-39,75-76H2,1-7H3,(H2,77,98)(H,84,99)(H,85,101)(H,86,100)(H,87,102)(H,88,108)(H,89,106)(H,90,103)(H,91,107)(H,92,104)(H,93,105)(H,94,109)(H,95,110)(H,111,112)(H4,78,79,82)(H4,80,81,83)/t43-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60+,61+/m1/s1
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = AGTSSZRZBSNTGQ-ITZCFHCWSA-N
|Section2={{Chembox Properties
| C=74 | H=115 | N=21 | O=17
| MolarMass=1570.8354
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
}}

Dynorphin B, also known as rimorphin,^[2] is a form of dynorphin and an endogenous opioid peptide with the amino acid sequence Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Gln-Phe-Lys-Val-Val-Thr. Dynorphin B is generated as a proteolyic cleavage product of leumorphin, which in turn is a cleavage product of preproenkephalin B (prodynorphin).{{Citation needed|date=April 2012}}

References

1. ^[https://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=16133806 Dynorphin B - Compound Summary], PubChem.
2. ^{{cite book|author=Paul V. Malven | title = Mammalian Neuroendocrinology | url = https://books.google.com/books?id=nZoRPQa_qTkC&pg=PA70 | accessdate = 22 April 2012 | date = 12 January 1993 | publisher = CRC Press | isbn = 978-0-8493-8757-9 | page = 70}}

3 : Neuropeptides|Kappa agonists|Opioid peptides

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See also

References