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词条 Ectoine synthase
释义

  1. References

{{enzyme
| Name = Ectoine synthase
| EC_number = 4.2.1.108
| CAS_number =
| IUBMB_EC_number = 4/2/1/108
| GO_code =
| image =
| width =
| caption =
}}

In enzymology, an ectoine synthase ({{EC number|4.2.1.108}}) is an enzyme that catalyzes the chemical reaction

N4-acetyl-L-2,4-diaminobutanoate L-ectoine + H2O

Hence, this enzyme has one substrate, N4-acetyl-L-2,4-diaminobutanoate, and two products, L-ectoine and H2O.

This enzyme belongs to the family of lyases, specifically the hydro-lyases, which cleave carbon-oxygen bonds. The systematic name of this enzyme class is N4-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming). Other names in common use include N-acetyldiaminobutyrate dehydratase, N-acetyldiaminobutanoate dehydratase, L-ectoine synthase, EctC, and 4-N-acetyl-L-2,4-diaminobutanoate hydro-lyase (L-ectoine-forming). This enzyme participates in glycine, serine and threonine metabolism.

References

  • {{cite journal | vauthors = Peters P, Galinski EA, Truper HG | last-author-amp = yes | date = 1990 | title = The biosynthesis of ectoine | journal = FEMS Microbiol. Lett. | volume = 71 | issue = 1–2 | pages = 157–162 | doi = 10.1111/j.1574-6968.1990.tb03815.x }}
  • {{cite journal | vauthors = Ono H, Sawada K, Khunajakr N | display-authors=etal | date = 1999 | title = Characterization of biosynthetic enzymes for ectoine as a compatible solute in a moderately halophilic eubacterium, Halomonas elongata | journal = J. Bacteriol. | volume = 181 | pages = 91–9 | pmid = 9864317 | issue = 1 | pmc = 103536 }}
  • {{cite journal | vauthors = Kuhlmann AU, Bremer E | date = 2002 | title = Osmotically regulated synthesis of the compatible solute ectoine in Bacillus pasteurii and related Bacillus spp | journal = Appl. Environ. Microbiol. | volume = 68 | pages = 772–83 | pmid = 11823218 | doi = 10.1128/AEM.68.2.772-783.2002 | issue = 2 | pmc = 126723 }}
  • {{cite journal | vauthors = Louis P, Galinski EA | title = Characterization of genes for the biosynthesis of the compatible solute ectoine from Marinococcus halophilus and osmoregulated expression in Escherichia coli | journal = Microbiology | volume = 143 | pages = 1141–9 | pmid = 9141677 | doi = 10.1099/00221287-143-4-1141 | issue = 4 | year = 1997 }}
{{Carbon-oxygen lyases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{4.2-enzyme-stub}}

2 : EC 4.2.1|Enzymes of unknown structure

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