| 词条 | EHNA |
| 释义 |
| verifiedrevid = 403603363 | IUPAC_name = 3-(6-aminopurin-9-yl)nonan-2-ol | image = EHNA.svg | width = 180 | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number = 59262-86-1 | ATC_prefix = | ATC_suffix = | PubChem = 3206 | DrugBank_Ref = {{drugbankcite|correct|drugbank}} | DrugBank = | ChEMBL_Ref = {{ebicite|correct|EBI}} | ChEMBL = 50378 | ChemSpiderID = 3094 | C=14 | H=23 | N=5 | O=1 | molecular_weight = 277.365 g/mol | smiles = CCCCCCC(C(C)O)n1cnc2c1ncnc2N | StdInChI=1S/C14H23N5O/c1-3-4-5-6-7-11(10(2)20)19-9-18-12-13(15)16-8-17-14(12)19/h8-11,20H,3-7H2,1-2H3,(H2,15,16,17) | StdInChIKey = IOSAAWHGJUZBOG-UHFFFAOYSA-N }}EHNA (erythro-9-(2-hydroxy-3-nonyl)adenine) is a potent adenosine deaminase inhibitor,[1] which also acts as a phosphodiesterase inhibitor that selectively inhibits phosphodiesterase type 2 (PDE2).[2][3] References1. ^{{cite web|title=Sigma Aldrich|url=http://www.sigmaaldrich.com/catalog/product/sigma/e114?lang=en®ion=US|accessdate=16 January 2013}} {{Phosphodiesterase inhibitors}}{{DEFAULTSORT:Ehna}}{{drug-stub}}2. ^{{cite journal | doi = 10.1016/0898-6568(95)00042-N | last1 = Podzuweit | first1 = T | last2 = Nennstiel | first2 = P | last3 = Muller | first3 = A | year = 1995 | title = Isozyme selective inhibition of cGMP-stimulated cyclic nucleotide phosphodiesterases by erythro-9-(2-hydroxy-3-nonyl) adenine | url = | journal = Cell Signal | volume = 7 | issue = 7| pages = 733–8 | pmid = 8519602 }} 3. ^{{cite journal | last1 = Méry | first1 = PF | last2 = Pavoine | first2 = C | last3 = Pecker | first3 = F | last4 = Fischmeister | first4 = R | year = 1995 | title = Erythro-9-(2-hydroxy-3-nonyl)adenine inhibits cyclic GMP-stimulated phosphodiesterase in isolated cardiac myocytes | url = | journal = Mol Pharmacol | volume = 48 | issue = 1| pages = 121–130 | pmid = 7623766 }} 3 : PDE2 inhibitors|Purines|Alcohols |
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