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词条 Etamivan
释义

  1. References

{{Drugbox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 447989190
| IUPAC_name = N,N-Diethyl-4-hydroxy-3-methoxybenzamide
| image = Ethamivan.svg
| width = 200
| tradename = Analepticon
| routes_of_administration =
| CAS_number_Ref = {{cascite|correct|??}}
| CAS_number = 304-84-7
| ATC_prefix = R07
| ATC_suffix = AB04
| PubChem = 9363
| DrugBank_Ref = {{drugbankcite|changed|drugbank}}
| DrugBank = DB08989
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 8996
| UNII_Ref = {{fdacite|correct|FDA}}
| UNII = M44O63YPV9
| KEGG_Ref = {{keggcite|correct|kegg}}
| KEGG = D04080
| C=12 | H=17 | N=1 | O=3
| molecular_weight = 223.268 g/mol
| smiles = CCN(CC)C(=O)C1=CC(=C(C=C1)O)OC
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI=1S/C12H17NO3/c1-4-13(5-2)12(15)9-6-7-10(14)11(8-9)16-3/h6-8,14H,4-5H2,1-3H3
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = BQJODPIMMWWMFC-UHFFFAOYSA-N
}}

Etamivan (INN, or ethamivan (USAN); trade names Analepticon and Vandid) is a respiratory stimulant drug[1] related to nikethamide. It was mainly used in the treatment of barbiturate overdose[2] and chronic obstructive pulmonary disease,[3] but has now largely fallen into disuse.

References

1. ^Hirsh K, Wang SC. Respiratory stimulant effects of ethamivan and picrotoxin. Journal of Pharmacology and Experimental Therapeutics. 1975 May;193(2):657-63.
2. ^Wheeldon PJ, Perry AW. The use of ethamivan in the treatment of barbiturate poisoning. Canadian Medical Association Journal. 1963 Jul 6;89:20-2.
3. ^Sproule BJ, Jans RL, Breitkreutz H, Mahon W. Effects of ethamivan in patients with chronic respiratory disease. Canadian Medical Association Journal. 1964 Dec 5;91:1203-8.
{{stimulants}}{{Other respiratory system products}}{{respiratory-system-drug-stub}}

5 : Stimulants|Respiratory agents|Phenols|Benzamides|Phenol ethers

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