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词条 Fenamic acid
释义

  1. References

{{chembox
| Verifiedfields = changed
| Watchedfields = changed
| verifiedrevid = 414204436
| ImageFile=Fenamic acid.png
| ImageSize=200px
| ImageFile1=Fenamic acid 3D ball.png
| ImageAlt1=Ball-and-stick model of fenamic acid
| IUPACName=2-(phenylamino)benzoic acid
| OtherNames=N-phenylanthranilic acid
|Section1={{Chembox Identifiers
| IUPHAR_ligand = 4182
| CASNo_Ref = {{cascite|correct|??}}
| CASNo=91-40-7
| ChEBI_Ref = {{ebicite|changed|EBI}}
| ChEBI = 34756
| ChEMBL_Ref = {{ebicite|changed|EBI}}
| ChEMBL = 23832
| SMILES=C1=CC=C(C=C1)NC2=CC=CC=C2C(=O)O
| PubChem = 4386
| ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}}
| ChemSpiderID = 4233
| InChI = 1/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16)
| InChIKey = ZWJINEZUASEZBH-UHFFFAOYAQ
| StdInChI_Ref = {{stdinchicite|changed|chemspider}}
| StdInChI = 1S/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16)
| StdInChIKey_Ref = {{stdinchicite|changed|chemspider}}
| StdInChIKey = ZWJINEZUASEZBH-UHFFFAOYSA-N
|Section2={{Chembox Properties
| Formula=C13H11NO2
| MolarMass=213.23 g/mol
| Appearance=
| Density=
| MeltingPt=
| BoilingPt=
| Solubility=
|Section3={{Chembox Hazards
| MainHazards=
| FlashPt=
| AutoignitionPt =
}}Fenamic acid is a molecule which, especially in its ester form, fenamate,[1]{{rp|458}} serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid. These drugs are commonly referred to as "anthranilic acid derivatives" or "fenamates" because fenamic acid is a derivative of anthranilic acid.[2]{{rp|235}}[3]{{rp|17}}[2]

References

1. ^Gupta, PK. Drug NomenclatureUnited States Adopted Names. Ch 27 in Remington: The Science and Practice of Pharmacy, Vol 1. Eds. David B. Troy, Paul Beringer. Lippincott Williams & Wilkins, 2006 {{ISBN|9780781746731}}
2. ^Sriram D, Yogeeswari P. [https://books.google.com/books?id=tUSLclf_NoQC&pg=PA235 Medicinal Chemistry, 2nd Edition]. Pearson Education India, 2010. {{ISBN|9788131731444}}
3. ^Auburn University course material. Jack DeRuiter, Principles of Drug Action 2, Fall 2002 1: Non-Steroidal Antiinflammatory Drugs (NSAIDS)
{{Anti-inflammatory and antirheumatic products}}{{Prostanoidergics}}

2 : Anthranilic acids|Nonsteroidal anti-inflammatory drugs

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