词条 | Fenamic acid |
释义 |
| Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 414204436 | ImageFile=Fenamic acid.png | ImageSize=200px | ImageFile1=Fenamic acid 3D ball.png | ImageAlt1=Ball-and-stick model of fenamic acid | IUPACName=2-(phenylamino)benzoic acid | OtherNames=N-phenylanthranilic acid |Section1={{Chembox Identifiers | IUPHAR_ligand = 4182 | CASNo_Ref = {{cascite|correct|??}} | CASNo=91-40-7 | ChEBI_Ref = {{ebicite|changed|EBI}} | ChEBI = 34756 | ChEMBL_Ref = {{ebicite|changed|EBI}} | ChEMBL = 23832 | SMILES=C1=CC=C(C=C1)NC2=CC=CC=C2C(=O)O | PubChem = 4386 | ChemSpiderID_Ref = {{chemspidercite|changed|chemspider}} | ChemSpiderID = 4233 | InChI = 1/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16) | InChIKey = ZWJINEZUASEZBH-UHFFFAOYAQ | StdInChI_Ref = {{stdinchicite|changed|chemspider}} | StdInChI = 1S/C13H11NO2/c15-13(16)11-8-4-5-9-12(11)14-10-6-2-1-3-7-10/h1-9,14H,(H,15,16) | StdInChIKey_Ref = {{stdinchicite|changed|chemspider}} | StdInChIKey = ZWJINEZUASEZBH-UHFFFAOYSA-N |Section2={{Chembox Properties | Formula=C13H11NO2 | MolarMass=213.23 g/mol | Appearance= | Density= | MeltingPt= | BoilingPt= | Solubility= |Section3={{Chembox Hazards | MainHazards= | FlashPt= | AutoignitionPt = }}Fenamic acid is a molecule which, especially in its ester form, fenamate,[1]{{rp|458}} serves as a parent structure for several nonsteroidal anti-inflammatory drugs (NSAIDs), including mefenamic acid, tolfenamic acid, flufenamic acid, and meclofenamic acid. These drugs are commonly referred to as "anthranilic acid derivatives" or "fenamates" because fenamic acid is a derivative of anthranilic acid.[2]{{rp|235}}[3]{{rp|17}}[2] References1. ^Gupta, PK. Drug NomenclatureUnited States Adopted Names. Ch 27 in Remington: The Science and Practice of Pharmacy, Vol 1. Eds. David B. Troy, Paul Beringer. Lippincott Williams & Wilkins, 2006 {{ISBN|9780781746731}} {{Anti-inflammatory and antirheumatic products}}{{Prostanoidergics}}2. ^1 Sriram D, Yogeeswari P. [https://books.google.com/books?id=tUSLclf_NoQC&pg=PA235 Medicinal Chemistry, 2nd Edition]. Pearson Education India, 2010. {{ISBN|9788131731444}} 3. ^Auburn University course material. Jack DeRuiter, Principles of Drug Action 2, Fall 2002 1: Non-Steroidal Antiinflammatory Drugs (NSAIDS) 2 : Anthranilic acids|Nonsteroidal anti-inflammatory drugs |
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