“Ferredoxin—nitrite reductase”的意思、由来-开放百科全书

词条

Ferredoxin—nitrite reductase

释义

Structural studies
References
Literature

{{enzyme
| Name = ferredoxin—nitrite reductase
| EC_number = 1.7.7.1
| CAS_number = 37256-44-3
| IUBMB_EC_number = 1/7/7/1
| GO_code = 0048307
| image =
| width =
| caption =
}}

In enzymology, a ferredoxin—nitrite reductase ({{EC number|1.7.7.1}}) is an enzyme that catalyzes the chemical reaction

NH₃ + 2 H₂O + 6 oxidized ferredoxin nitrite + 6 reduced ferredoxin + 7 H⁺

The 3 substrates of this enzyme are NH₃, H₂O, and oxidized ferredoxin, whereas its 3 products are nitrite, reduced ferredoxin, and H⁺.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with an iron-sulfur protein as acceptor. The systematic name of this enzyme class is ammonia:ferredoxin oxidoreductase. This enzyme participates in nitrogen metabolism and nitrogen assimilation. It has 3 cofactors: iron, Siroheme, and Iron-sulfur.

This enzyme can use many different isoforms of ferredoxin. In photosynthesizing tissues, it uses ferredoxin that is reduced by PSI and in the root it uses a form of ferredoxin (FdIII) that has a less negative midpoint potential and can be reduced easily by NADPH.^[1]

Structural studies

As of late 2007, 3 structures have been solved for this class of enzymes, with PDB accession codes {{PDB link|1ZJ8}}, {{PDB link|1ZJ9}}, and {{PDB link|2AKJ}}.

References

1. ^{{Cite journal | last1 = Hanke | first1 = G. T. | last2 = Kimata-Ariga | first2 = Y. | last3 = Taniguchi | first3 = I. | last4 = Hase | first4 = T. | title = A Post Genomic Characterization of Arabidopsis Ferredoxins | doi = 10.1104/pp.103.032755 | journal = Plant Physiology | volume = 134 | issue = 1 | pages = 255–264 | year = 2004 | pmid = 14684843| pmc =316305 }}

Literature

{{cite journal |vauthors=Joy KW, Hageman RH | year = 1966 | title = The purification and properties of nitrite reductase from higher plants, and its dependence on ferredoxin | journal = Biochem. J. | volume = 100 | pages = 263–73 | pmid = 4381617 | issue = 1 | pmc = 1265119 }}
{{cite journal |vauthors=Ramirez JM, Del Campo FF, Paneque A, Losada M | year = 1966 | title = Ferredoxin-nitrite reductase from spinach | journal = Biochim. Biophys. Acta | volume = 118 | pages = 58–71 | pmid = 5954064 | issue = 1 | doi=10.1016/s0926-6593(66)80144-3}}
{{cite journal |vauthors=Zumft WG, Paneque A, Aparicio PJ, Losada M | year = 1969 | title = Mechanism of nitrate reduction in Chlorella | journal = Biochem. Biophys. Res. Commun. | volume = 36 | pages = 980–6 | pmid = 4390523 | doi = 10.1016/0006-291X(69)90300-3 | issue = 6 }}

{{refend}}{{Nitrogenous donor oxidoreductases}}{{Enzymes}}{{Portal bar|Molecular and Cellular Biology|border=no}}{{DEFAULTSORT:Ferredoxin-nitrite reductase}}{{1.7-enzyme-stub}}

5 : EC 1.7.7|Iron enzymes|Siroheme enzymes|Iron-sulfur enzymes|Enzymes of known structure

随便看

开放百科全书收录14589846条英语、德语、日语等多语种百科知识，基本涵盖了大多数领域的百科知识，是一部内容自由、开放的电子版国际百科全书。