“Flavone synthase”的意思、由来-开放百科全书

词条

Flavone synthase

释义

References

{{enzyme
| Name = Flavone synthase
| EC_number = 1.14.11.22
| CAS_number = 138263-98-6
| IUBMB_EC_number = 1/14/11/22
| GO_code =
| image =
| width =
| caption =
}}

In enzymology, a flavone synthase ({{EC number|1.14.11.22}}) is an enzyme that catalyzes the chemical reaction

a flavanone + 2-oxoglutarate + O₂ a flavone + succinate + CO₂ + H₂O

The 3 substrates of this enzyme are flavanone, 2-oxoglutarate, and O₂, whereas its 4 products are flavone, succinate, CO₂, and H₂O.

This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with 2-oxoglutarate as one donor, and incorporation of one atom o oxygen into each donor. The systematic name of this enzyme class is flavanone,2-oxoglutarate:oxygen oxidoreductase (dehydrating). This enzyme participates in flavonoid biosynthesis and isoflavonoid biosynthesis.

References

{{cite journal | vauthors = Martens S, Forkmann G, Matern U, Lukacin R | date = 2001 | title = Cloning of parsley flavone synthase I | journal = Phytochemistry | volume = 58 | pages = 43–6 | pmid = 11524111 | doi = 10.1016/S0031-9422(01)00191-1 | issue = 1 }}
{{cite journal | author = G, Martens S | date = 2001 | title = Purification and antigenicity of flavone synthase I from irradiated parsley cells | journal = Arch. Biochem. Biophys. | volume = 393 | pages = 177–83 | pmid = 11516175 | doi = 10.1006/abbi.2001.2491 | last2 = Matern | first2 = U | last3 = Junghanns | first3 = KT | last4 = Heskamp | first4 = ML | last5 = Britsch | first5 = L | last6 = Forkmann | first6 = G | last7 = Martens | first7 = S | issue = 1 }}
{{cite journal | vauthors = Martens S, Forkmann G, Britsch L, Wellmann F, Matern U, Lukacin R | date = 2003 | title = Divergent evolution of flavonoid 2-oxoglutarate-dependent dioxygenases in parsley | journal = FEBS Lett. | volume = 544 | pages = 93–8 | pmid = 12782296 | doi = 10.1016/S0014-5793(03)00479-4 | issue = 1-3 }}

3 : EC 1.14.11|Enzymes of unknown structure|Flavones metabolism

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