| 词条 | Fluprednidene |
| 释义 |
| Verifiedfields = | Watchedfields = | verifiedrevid = | IUPAC_name = (8S,9R,10S,11S,13S,14S,17R)-9-Fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-16-methylidene-7,8,11,12,14,15-hexahydro-6H-cyclopenta[a]phenanthren-3-one | image = Fluprednidene.svg | width = | tradename = | pregnancy_AU = | pregnancy_US = | pregnancy_category = | legal_AU = | legal_CA = | legal_UK = | legal_US = | legal_status = | routes_of_administration = | bioavailability = | protein_bound = | metabolism = | elimination_half-life = | excretion = | CAS_number_Ref = | CAS_number = 2193-87-5 | CAS_supplemental = | class = Corticosteroid; Glucocorticoid | ATC_prefix = | ATC_suffix = | ATC_supplemental = | PubChem = 11794741 | IUPHAR_ligand = | DrugBank_Ref = | DrugBank = | ChemSpiderID_Ref = | ChemSpiderID = 9969413 | UNII = FA517NS3N7 | KEGG = | ChEBI = | ChEMBL = | C=22 | H=27 | F=1 | O=5 | SMILES = C[C@]12C[C@@H]([C@]3([C@H]([C@@H]1CC(=C)[C@@]2(C(=O)CO)O)CCC4=CC(=O)C=C[C@@]43C)F)O | StdInChI_Ref = | StdInChI = 1S/C22H27FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,15-17,24,26,28H,1,4-5,8,10-11H2,2-3H3/t15-,16-,17-,19-,20-,21-,22-/m0/s1 | StdInChIKey_Ref = | StdInChIKey = YVHXHNGGPURVOS-SBTDHBFYSA-N | synonyms = Fluprednylidene; 9α-Fluoro-11β,17α,21-trihydroxy-16-methylenepregna-1,4-diene-3,20-dione }}Fluprednidene, also known as fluprednylidene, is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2][3] An acetate ester of fluprednidene, fluprednidene acetate, in contrast, has been marketed.[1][2][3] References1. ^1 {{cite book|author=J. Elks|title=The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies|url=https://books.google.com/books?id=0vXTBwAAQBAJ&pg=PA570|date=14 November 2014|publisher=Springer|isbn=978-1-4757-2085-3|pages=570–}} {{Glucocorticoid receptor modulators}}{{steroid-stub}}2. ^1 {{cite book|title=Index Nominum 2000: International Drug Directory|url=https://books.google.com/books?id=5GpcTQD_L2oC&pg=PA463|year=2000|publisher=Taylor & Francis|isbn=978-3-88763-075-1|pages=463–}} 3. ^1 {{cite book|author=Cynthia A. Challener|title=Chiral Drugs|url=https://books.google.com/books?id=hyhtAAAAMAAJ|date=1 December 2001|publisher=Wiley|isbn=978-0-566-08411-9|page=490}} 5 : Diketones|Fluoroarenes|Glucocorticoids|Pregnanes|Triols |
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